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Open Access577-nm high-power optically pumped semiconductor laser is safe and effective in the treatment of inflammatory acne: a prospective, single-center, split-face comparative study
This study aimed to appraise the efficacy of a 577-nm high-power optically pumped semiconductor laser (HOPSL) for the treatment of inflammatory acne.
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Open AccessStability and reproducibility of 6013 deep inspiration breath-holds in left-sided breast cancer
Patients with left-sided breast cancer frequently receive deep inspiration breath-hold (DIBH) radiotherapy to reduce the risk of cardiac side effects. The aim of the present study was to analyze intra-breath-h...
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Open AccessTreatment of onychomycosis using a 1064-nm diode laser with or without topical antifungal therapy: a single-center, retrospective analysis in 56 patients
Currently available treatment options for onychomycosis such as topical and systemic antifungals are often of limited efficacy, difficult to administer or associated with relevant side effects. Non-ablative la...
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Polyfunctionality of CD4+ T lymphocytes is increased after chemoradiotherapy of head and neck squamous cell carcinoma
For head and neck squamous cell cancer (HNSCC), standard therapy consists of surgery, radiation, and/or chemotherapy. Antineoplastic immunotherapy could be an option in an adjuvant setting and is already in pa...
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Strahlentherapie – ein Update
Dieser Review soll die wichtigsten neuen Studien zur Behandlung des primär operablen Mammakarzinoms, die zu einer Änderung der AGO(Arbeitsgemeinschaft Onkologie)-Leitlinien geführt haben, zusammenfassen und er...
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Erratum to: DEGRO practical guidelines for radiotherapy of breast cancer V
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Bestrahlung der Mamma nach brusterhaltender Operation
Nach brusterhaltender Operation ist eine Nachbestrahlung indiziert. Es stellt sich die Frage, wie stark ausgeprägt die Effekte der Bestrahlung auf das Lokalrezidivrisiko und Überleben sind und ob nicht bei bes...
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Strahleninduzierter Morbus Favre-Racouchot
Ein 71-jähriger Mann stellte sich in unserer dermatologischen Abteilung mit stigmatisierenden Hautveränderungen an Nase und Wangen vor. Der Patient hatte vor dem Auftreten der Hautveränderungen eine Operation ...
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Breast cancer in the lower jaw after reconstructive surgery with a pectoralis major myocutaneous flap (PMMC) - A case report
For head and neck as well as for oromaxillofacial surgery, the use of the pectoralis major myocutaneous (PMMC) flap is a standard reconstructive technique after radical surgery for cancers in this region. We r...
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Sunitinib induced pyoderma gangrenosum-like ulcerations
Pyoderma gangrenosum is a non-infectious neutrophilic skin disease commonly associated with underlying systemic diseases. Histopathological and laboratory diagnostics are unspecific in the majority of the case...
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Fallbasiertes interaktives „PACS-learning“
Humanmedizinische Curricula unterliegen derzeit einem Reformprozess mit Etablierung übergeordneter Lernziele, wie z. B. der diagnostischen, therapeutischen und präventiven Kompetenz. Damit verbunden sind eine ...
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Trimodal therapy in squamous cell carcinoma of the esophagus
Patients with ESCC (squamous cell carcinoma of the esophagus) are most commonly diagnosed with locally advanced tumor stages. Early metastatic disease and late diagnosis are common reasons responsible for this...
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The role of neoadjuvant and adjuvant treatment for adenocarcinoma of the upper gastrointestinal tract
Both locally advanced adenocarcinoma of the stomach and gastro-esophageal junction are associated with poor prognosis due to the lack of effective treatment. Recently multimodal treatment consisting of neoadju...
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Dendritic cell generation and CD4+CD25HIGHFOXP3+ regulatory T cells in human head and neck carcinoma during Radio-chemotherapy
Regulatory T cells (Treg) and dendritic cells (DC) play an important role in tumor immunity and immune escape. However, their interplay and the effects of anti-cancer therapy on the human immune system are lar...
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Fulminant Staphylococcus lugdunensis septicaemia following a pelvic varicella-zoster virus infection in an immune-deficient patient: a case report
The deadly threat of systemic infections with coagulase negative Staphylococcus lugdunensis despite an appropriate antibiotic therapy has only recently been recognized. The predominant infectious focus observed s...
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Extranodal diffuse non hodgkin lymphoma in the thigh
Diffuse large B-cell lymphoma usually starts as a rapidly growing mass in an internal lymph node and can grow in other areas such as the bone or intestines. About 1/3 of these lymphomas are confined to one par...
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In vitro chemosensitivity of head and neck cancer cell lines
Systemic treatment of head and neck squamous cell carcinoma (HNSCC) includes a variety of antineoplastic drugs. However, drug-resistance interferes with the effectiveness of chemotherapy. Preclinical testing m...
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Methylated APC and GSTP1 genes in serum DNA correlate with the presence of circulating blood tumor cells and are associated with a more aggressive and advanced breast cancer disease
Tumor-related methylated DNA and circulating tumor cells (CTC) in the peripheral blood might be of prognostic importance in breast cancer. Thus, the aim of our study was to examine free methylated DNA and CTC ...
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Identification of candidate genes with pro-apoptotic properties by functional screening of randomly fragmented C DNA libraries
The sequences of many genomes are available; therefore, relevant methods are needed for rapid and efficient identification of functional genes. The ability of tumour cells to resist apoptosis induced by antica...
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Bendamustine in patients with relapsed or refractory multiple myeloma
In patients with multiple myeloma, bendamustine monotherapy is effective as 1st and 2nd line therapy. However, data for patients with advanced multiple myeloma is rare.