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  1. Article

    Open Access

    Evolution of lysine-specific demethylase 1 and REST corepressor gene families and their molecular interaction

    Lysine-specific demethylase 1A (LSD1) binds to the REST corepressor (RCOR) protein family of corepressors to erase transcriptionally active marks on histones. Functional diversity in these complexes depends on...

    Montserrat Olivares-Costa, Gianluca Merello Oyarzún… in Communications Biology (2023)

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  2. Article

    Open Access

    Revealing RCOR2 as a regulatory component of nuclear speckles

    Nuclear processes such as transcription and RNA maturation can be impacted by subnuclear compartmentalization in condensates and nuclear bodies. Here, we characterize the nature of nuclear granules formed by R...

    Carlos Rivera, Daniel Verbel-Vergara, Duxan Arancibia… in Epigenetics & Chromatin (2021)

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  3. No Access

    Article

    The Exocyst Component Exo70 Modulates Dendrite Arbor Formation, Synapse Density, and Spine Maturation in Primary Hippocampal Neurons

    Neurons are highly polarized cells displaying an elaborate architectural morphology. The design of their dendritic arborization and the distribution of their synapses contribute importantly to information proc...

    Matías Lira, Duxan Arancibia, Patricio R. Orrego… in Molecular Neurobiology (2019)