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Article
Genotypic characterization of novel S-DEL variants of porcine epidemic diarrhea virus identified in South Korea
The highly pathogenic genotype 2b (HP-G2b) of porcine epidemic diarrhea virus (PEDV), which caused a pandemic in 2013–2014, evolved in South Korea and became endemic, affecting the domestic pig industry. This ...
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Article
Coinfection with porcine epidemic diarrhea virus and Clostridium perfringens type A enhances disease severity in weaned pigs
Clostridium perfringens is a constituent of the normal gut microbiome in pigs; however, it can potentially cause pre- and post-weaning diarrhea. Nevertheless, the importance of this bacterium as a primary pathoge...
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Article
Trypsin enhances SARS-CoV-2 infection by facilitating viral entry
Coronaviruses infect cells by cytoplasmic or endosomal membrane fusion, driven by the spike (S) protein, which must be primed by proteolytic cleavage at the S1/S2 furin cleavage site (FCS) and the S2′ site by ...
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Article
Development of the new microsatellite markers of Lucilia sericata (Diptera: Calliphoridae) from Korea
Lucilia sericata is a medical and veterinary important insect species because its larvae feed on tissues of vertebrates including humans. Very few microsatellite makers have been reported from the species to illu...
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Article
Open AccessMutant-selective topologic conversion facilitates selective degradation of a pathogenic prion isoform
Regulating protein import across the endoplasmic reticulum (ER) membrane occasionally results in the synthesis of topologically unnatural variants, and their accumulation often leads to proteotoxicity. However...
