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    Article

    Clinical Pharmacokinetics of Tretinoin

    Recent reports of the dramatic antitumour effect of tretinoin (all-trans retinoic acid) in patients with acute promyelocytic leukaemia (APL) have generated a great deal of interest in the use of this drug as a ch...

    Dr Mario B. Regazzi, Isabella Iacona, Cristina Gervasutti in Clinical Pharmacokinetics (1997)

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    Article

    Time-Dependent Kinetics of Tretinoin in Chronic Myelogenous Leukaemia during Intermittent Dose Scheduling

    Objective: This study investigated the pharmacokinetics of tretinoin during alternating cycles of 1 week of tretinoin treatment and 1 week drug-free in patients with Ph1+ chronic myelogenous leuk...

    Dr Mario B. Regazzi, D. Russo, I. Iacona, S. Sacchi in Clinical Drug Investigation (1998)