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  1. No Access

    Article

    Time-Dependent Kinetics of Tretinoin in Chronic Myelogenous Leukaemia during Intermittent Dose Scheduling

    Objective: This study investigated the pharmacokinetics of tretinoin during alternating cycles of 1 week of tretinoin treatment and 1 week drug-free in patients with Ph1+ chronic myelogenous leuk...

    Dr Mario B. Regazzi, D. Russo, I. Iacona, S. Sacchi… in Clinical Drug Investigation (1998)

  2. No Access

    Article

    Clinical Pharmacokinetics of Tretinoin

    Recent reports of the dramatic antitumour effect of tretinoin (all-trans retinoic acid) in patients with acute promyelocytic leukaemia (APL) have generated a great deal of interest in the use of this drug as a ch...

    Dr Mario B. Regazzi, Isabella Iacona, Cristina Gervasutti… in Clinical Pharmacokinetics (1997)