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Article
Open AccessCPI motif interaction is necessary for cap** protein function in cells
Cap** protein (CP) has critical roles in actin assembly in vivo and in vitro. CP binds with high affinity to the barbed end of actin filaments, blocking the addition and loss of actin subunits. Heretofore, mode...
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Article
Erratum: Cap** protein regulators fine-tune actin assembly dynamics
Nature Reviews Molecular Cell Biology 15, 677–689 (2014) On page 684 of the above article, there was a mistake in Figure 3b: the PH domain of CARMIL preferentially binds to monophosphorylated membrane lipids r...
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Article
Cap** protein regulators fine-tune actin assembly dynamics
Cap** protein (CP) is a major regulator of actin assembly dynamics via the cap** of actin filament barbed ends. The cap** activity of CP can be regulated...
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Article
Barbed ends rule
To explore their surroundings, cells use probes of various shapes. Whether the probes are broad and flat, or long and thin, seems to be regulated by proteins at the growing ends of actin filaments.
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Article
Actin puts on the squeeze
Compensatory endocytosis retrieves membrane and proteins that are deposited at the plasma membrane during exocytosis. A new study reveals that actin filaments assemble into structures that compress membrane-bo...
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Article
Transcription by single molecules of RNA polymerase observed by light microscopy
THE kinetics of transcription by Escherichia coli RNA polymerase relate directly to the regulation of transcription and to the properties of processive enzymes in general1, but analysis of RNA polymerase movement...
