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  1. Article

    Open Access

    The effect of food on the pharmacokinetics of oral ibrutinib in healthy participants and patients with chronic lymphocytic leukemia

    To assess ibrutinib pharmacokinetics under fasted and fed conditions, impact of food-intake timing, and the safety and tolerability.

    Jan de Jong, Juthamas Sukbuntherng, Donna Skee… in Cancer Chemotherapy and Pharmacology (2015)

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    Article

    Pharmacokinetic, Pharmacodynamic and Covariate Analysis of Subcutaneous Versus Intravenous Administration of Bortezomib in Patients with Relapsed Multiple Myeloma

    The proteasome inhibitor bortezomib is approved for the treatment of multiple myeloma (MM) and, in the US, for the treatment of mantle cell lymphoma following at least one prior therapy; the recommended dose a...

    Philippe Moreau, Ievgenii I. Karamanesht, Natalia Domnikova… in Clinical Pharmacokinetics (2012)