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Article
Molecular classification of papillary thyroid carcinoma: distinct BRAF, RAS, and RET/PTC mutation-specific gene expression profiles discovered by DNA microarray analysis
Thyroid cancer poses a significant clinical challenge, and our understanding of its pathogenesis is incomplete. To gain insight into the pathogenesis of papillary thyroid carcinoma, transcriptional profiles of...
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Article
The CuA domain of Thermus thermophilus ba3-type cytochrome c oxidase at 1.6 Å resolution
The structure of the CuA-containing, extracellular domain of Thermus thermophilus ba3-type cytochrome c oxidase has been determined to 1.6 Å resolution using multiple X-ray wavelength anomalous dispersion (MAD). ...
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Article
Reaction of mercurials with the CuA center in the soluble fragment of cytochrome ba 3 subunit II from Thermus thermophilus
Optical absorption, EPR and electrospray ionization mass spectrometries were used to characterize a stoichiometric reaction between mercurials and the soluble ba 3–CuA protein from Thermus thermophilus. Either o...
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Article
Electrochemistry of the CuA domain of Thermus thermophilus cytochrome ba 3
The electrochemistry of a water-soluble fragment from the CuA domain of Thermus thermophilus cytochrome ba 3 has been investigated. At 25 °C, CuA exhibits a reversible reduct...