31 Result(s)
within
DongDong Wang
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessDisruption of TIGAR-TAK1 alleviates immunopathology in a murine model of sepsis
Macrophage-orchestrated inflammation contributes to multiple diseases including sepsis. However, the underlying mechanisms remain to be defined clearly. Here, we show that macrophage TP53-induced glycolysis an...
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Open AccessThe formation of unsaturated IrOx in SrIrO3 by cobalt-do** for acidic oxygen evolution reaction
Electrocatalytic water splitting is a promising route for sustainable hydrogen production. However, the high overpotential of the anodic oxygen evolution reaction poses significant challenge. SrIrO3-based perovsk...
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Article
Open AccessWater-stable boroxine structure with dynamic covalent bonds
Boroxines are significant structures in the production of covalent organic frameworks, anion receptors, self-healing materials, and others. However, their utilization in aqueous media is a formidable task due ...
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Open AccessInsights into vehicle conflicts based on traffic flow dynamics
The utilization of traffic conflict indicators is crucial for assessing traffic safety, especially when the crash data is unavailable. To identify traffic conflicts based on traffic flow characteristics across...
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Open AccessThe characteristic analysis of phase-controlled array thermo-acoustic emission with multiple emitting surfaces
Thermo-acoustic (TA) ultrasound, particularly when combined with phased-controlled array technology, has garnered significant interest in the past decade due to its numerous advantages. This paper establishes ...
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Open AccessAssessment of early diabetic retinopathy severity using ultra-widefield Clarus versus conventional five-field and ultra-widefield Optos fundus imaging
To compare early diabetic retinopathy (DR) severity level and the abilities in detecting early DR lesions among conventional five-field, ultrawide-field (UWF) Optos, and UWF Clarus fundus imaging methods. This...
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Article
Open AccessCucurbit[8]uril-based water-dispersible assemblies with enhanced optoacoustic performance for multispectral optoacoustic imaging
Organic small-molecule contrast agents have attracted considerable attention in the field of multispectral optoacoustic imaging, but their weak optoacoustic performance resulted from relatively low extinction ...
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Article
Open AccessGDF15 promotes weight loss by enhancing energy expenditure in muscle
Caloric restriction that promotes weight loss is an effective strategy for treating non-alcoholic fatty liver disease and improving insulin sensitivity in people with type 2 diabetes1. Despite its effectiveness, ...
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Open AccessMicrobial synthesis of Prussian blue for potentiating checkpoint blockade immunotherapy
Cancer immunotherapy is revolutionizing oncology. The marriage of nanotechnology and immunotherapy offers a great opportunity to amplify antitumor immune response in a safe and effective manner. Here, electroc...
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Article
Open AccessBile metabolites as diagnostic biomarkers for perihilar cholangiocarcinoma
It is difficult to directly obtain pathological diagnosis of perihilar cholangiocarcinoma (pCCA). Analysis of bile in the pCCA microenvironment, based on metabolomics and statistical methods, can help in clini...
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Article
Open AccessSulforaphane ameliorates bisphenol A-induced hepatic lipid accumulation by inhibiting endoplasmic reticulum stress
The aim of the present study was to investigate the role of endoplasmic reticulum (ER) stress in bisphenol A (BPA) – induced hepatic lipid accumulation as well as the protective effects of Sulforaphane (SFN) i...
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Open AccessNanozyme-reinforced hydrogel as a H2O2-driven oxygenerator for enhancing prosthetic interface osseointegration in rheumatoid arthritis therapy
Stem cell-based therapy has drawn attention for enhancing the osseointegration efficiency after joint replacement in the rheumatoid arthritis (RA). However, therapeutic efficacy of this approach is threatened ...
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Open AccessOptimizing the Dryland Sheet Erosion equation in South China
Optimisation of models applied in sheet erosion equations could facilitate effective management of sheet erosion in the field, and sustainable agricultural production. To optimise the characterisation of sheet...
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Open AccessSimulation study on the indirect effect of sulfate on the summer climate over the eastern China monsoon region
In this study, we designed a sensitivity test using the half number concentration of sulfate in the nucleation calculation process to study the aerosol-cloud interaction (ACI) of sulfate on clouds, precipitati...
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Article
Open AccessInteraction between multi-walled carbon nanotubes and propranolol
Carbon nanotubes could accumulate in organism and have a negative impact on the structure and function of the ecosystem when they were discharged into environment. Furthermore, it will affect the migration and...
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Open AccessAn open source and reduce expenditure ROS generation strategy for chemodynamic/photodynamic synergistic therapy
The therapeutic effect of reactive oxygen species (ROS)-involved cancer therapies is significantly limited by shortage of oxy-substrates, such as hypoxia in photodynamic therapy (PDT) and insufficient hydrogen...
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Article
Open AccessColor-tunable ultralong organic room temperature phosphorescence from a multicomponent copolymer
Functional materials displaying tunable emission and long-lived luminescence have recently emerged as a powerful tool for applications in information encryption, organic electronics and bioelectronics. Herein,...
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Open AccessSelf-assembled single-atom nanozyme for enhanced photodynamic therapy treatment of tumor
Hypoxia of solid tumor compromises the therapeutic outcome of photodynamic therapy (PDT) that relies on localized O2 molecules to produce highly cytotoxic singlet oxygen (1O2) species. Herein, we present a safe a...
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Open AccessEffects of sea salt aerosols on precipitation and upper troposphere/lower stratosphere water vapour in tropical cyclone systems
The effects of sea salt aerosols (SSA) on cloud microphysical processes, precipitation, and upper troposphere/lower stratosphere water vapour in tropical cyclones were studied with the Weather Research and For...
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Open AccessMajor vault protein suppresses obesity and atherosclerosis through inhibiting IKK–NF-κB signaling mediated inflammation
Macrophage-orchestrated, low-grade chronic inflammation plays a pivotal role in obesity and atherogenesis. However, the underlying regulatory mechanisms remain incompletely understood. Here, we identify major ...
