221 Result(s)
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Open AccessArtificial intelligence-based graded training of pulmonary nodules for junior radiology residents and medical imaging students
To evaluate the efficiency of artificial intelligence (AI)-assisted diagnosis system in the pulmonary nodule detection and diagnosis training of junior radiology residents and medical imaging students.
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Open AccessTargeting CXCR4/CXCL12 axis via [177Lu]Lu-DOTAGA.(SA.FAPi)2 with CXCR4 antagonist in triple-negative breast cancer
Radiopharmaceutical therapies targeting fibroblast activation protein (FAP) have shown promising efficacy against many tumor types. But radiopharmaceuticals alone in most cases are insufficient to completely e...
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Di-caffeoylquinic acid: a potential inhibitor for amyloid-beta aggregation
Alzheimer's disease (AD) remains a challenging neurodegenerative disorder with limited therapeutic success. Traditional Chinese Medicine (TCM), as a promising new source for AD, still requires further explorat...
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Inertinite in coal and its geoenvironmental significance: Insights from AI and big data analysis
Inertinite, as an important and abundant maceral group in coal, is critical for the study of palaeowildfires and their roles in the Earth’s ecosystems. Recently, there has been a significant amount of research...
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Frequency convergence characteristics of lumped mass Galerkin meshfree methods
Due to the considerable complexity of meshfree approximants, there still lacks a rational theoretical estimate on the frequency accuracy of lumped mass meshfree methods. In this study, a detailed theoretical a...
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Open AccessDisruption of TIGAR-TAK1 alleviates immunopathology in a murine model of sepsis
Macrophage-orchestrated inflammation contributes to multiple diseases including sepsis. However, the underlying mechanisms remain to be defined clearly. Here, we show that macrophage TP53-induced glycolysis an...
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Open AccessLysosomal dysfunction and overload of nucleosides in thymidine phosphorylase deficiency of MNGIE
Inherited deficiency of thymidine phosphorylase (TP), encoded by TYMP, leads to a rare disease with multiple mitochondrial DNA (mtDNA) abnormalities, mitochondrial neurogastrointestinal encephalomyopathy (MNGIE)....
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Open AccessCorrelation of meniscus tear type with synovial inflammation and the therapeutic potential of docosapentaenoic acid
Synovitis, characterized by inflammation of the synovial membrane, is commonly induced by meniscus tears. However, significant differences in inflammatory responses and the key inflammatory mediators of synovi...
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Perovskite Structure LaNi0.5Fe0.5O3 Electrocatalyst for Rechargeable Li-O2 Batteries
Develo** efficient O2 electrocatalyst is crucial for lithium-oxygen (Li-O2) batteries (LOBs). Among various catalysts, perovskite oxides have exhibited diverse catalytic activity owing to their low synthetic co...
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Article
Association of preoperative aneurysmal wall enhancement with relief of chronic headache after surgical clip** of unruptured intracranial aneurysms
To investigate the association between chronic headache outcome and aneurysmal wall enhancement (AWE) on high-resolution vessel wall imaging (HR-VWI) in patients with unruptured intracranial aneurysms (UIAs) w...
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Open AccessThe formation of unsaturated IrOx in SrIrO3 by cobalt-do** for acidic oxygen evolution reaction
Electrocatalytic water splitting is a promising route for sustainable hydrogen production. However, the high overpotential of the anodic oxygen evolution reaction poses significant challenge. SrIrO3-based perovsk...
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5G Integrated User Downlink Adaptive Transmission Scheme for Low Earth Orbit Satellite Internet Access Network
After the low-earth orbit (LEO) satellite Internet has gone through the two stages of competing with the terrestrial network and supplementing the terrestrial network, it has begun to enter the third stage of ...
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Genetic relationship between formation, accumulation and migration and dispersion of peat materials in Paleogene–Take the Qiongdongnan Basin as an example
Coal-type source rocks include both coal and terrigenous marine source rocks. By studying the distribution of secondary depressions, uplifts, as well as the characteristics of peat formation and accumulation i...
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Astronomical influence of the development of Paleogene thin coal seam groups in offshore Lacustrine basins: A case study of the Zhu I Depression’s En** Formation located in the northern South China Sea
The development of the Paleogene coal seams in China’s offshore basin areas generally had the characteristics of coal measures with large thicknesses, large numbers of coal seams, thin single coal seams, poor ...
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Formation environment and hydrocarbon potential of the Paleogene En** Formation coal measures in the Zhu I Depression of northern South China Sea
The coal-measure source rock in the Chinese sea area plays a significant role as a hydrocarbon source rock, with its genetic environment, development and distribution, and hydrocarbon generation potential serv...
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An aspect ratio dependent lumped mass formulation for serendipity finite elements with severe side-length discrepancy
The frequency solutions of finite elements may significantly deteriorate as the mesh aspect ratios become large, which implies a severe element side-length discrepancy. In this work, an aspect ratio dependent ...
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Article
An insight to treat cardiovascular diseases through phytochemicals targeting PPAR-α
Peroxisome proliferator-activated receptor-α (PPAR-α) belonging to the nuclear hormone receptor superfamily is a promising target for CVDs which mechanistically improves the production of high-density lipid as...
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Open AccessWater-stable boroxine structure with dynamic covalent bonds
Boroxines are significant structures in the production of covalent organic frameworks, anion receptors, self-healing materials, and others. However, their utilization in aqueous media is a formidable task due ...
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Mitochondrial myopathy without extraocular muscle involvement: a unique clinicopathologic profile
Mitochondrial myopathy without extraocular muscles involvement (MiMy) represents a distinct form of mitochondrial disorder predominantly affecting proximal/distal or axial muscles, with its phenotypic, genotyp...
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Open AccessInsights into vehicle conflicts based on traffic flow dynamics
The utilization of traffic conflict indicators is crucial for assessing traffic safety, especially when the crash data is unavailable. To identify traffic conflicts based on traffic flow characteristics across...