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Article
Open Access“On-Water” accelerated dearomative cycloaddition via aquaphotocatalysis
Sulfur(VI) fluoride exchange (SuFEx) has emerged as an innovative click chemistry to harness the pivotal connectivity of sulfonyl fluorides. Synthesizing such alkylated S(VI) molecules through a straightforwar...
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Article
Fertility and the oil curse
The paper empirically investigates whether oil abundance affects fertility in a panel of develo** and developed countries for 1970–2020. The exploration sheds light into why poor develo** economies rich in...
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Article
Open AccessComparative efficacy and safety of subcutaneous infliximab and vedolizumab in patients with Crohn’s disease and ulcerative colitis included in randomised controlled trials
While indirect comparison of infliximab (IFX) and vedolizumab (VDZ) in adults with Crohn’s disease (CD) or ulcerative colitis (UC) shows that IFX has better effectiveness during induction, and comparable effic...
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Article
The moderating role of financial development in the nexus between population aging and saving
The paper empirically investigates the saving consequence of population aging, an issue that is important for policymaking and still far from uncontroversial. Rather than providing another piece of evidence to...
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Article
Open AccessManufacturing of stretchable substrate with biaxial strain control for highly-efficient stretchable solar cells and displays
There has been significant research focused on the development of stretchable materials that can provide a large area with minimal material usage for use in solar cells and displays. However, most materials ex...
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Article
Open AccessTargeting FLT3-TAZ signaling to suppress drug resistance in blast phase chronic myeloid leukemia
Although the development of BCR::ABL1 tyrosine kinase inhibitors (TKIs) rendered chronic myeloid leukemia (CML) a manageable condition, acquisition of drug resistance during blast phase (BP) progression remain...
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Article
Parametric study of a projectile launched by a compressed air cannon
The principle of the compressed air cannon is that compressed air in the reservoir expands rapidly to propel the projectile. Previous studies assume that the tube pressure in front of the projectile is constan...
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Article
A deep-learning method using single phantom to enhance megavoltage image quality for patient positioning in chest radiotherapy: a feasibility study
Image-guided radiation treatment (IGRT) is essential for verifying patient positioning during modern radiotherapy. Although megavoltage digital radiographs (MV-DR) are available on most therapeutic linear acce...
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Article
Open AccessSubcutaneous Infliximab Monotherapy Versus Combination Therapy with Immunosuppressants in Inflammatory Bowel Disease: A Post Hoc Analysis of a Randomised Clinical Trial
Whether benefits and risks of intravenous (IV) infliximab combotherapy with immunosuppressants versus infliximab monotherapy apply to subcutaneous (SC) infliximab is unknown. This post hoc analysis of a pivota...
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Article
Gut microbiota modulation via short-term administration of potential probiotic kefir yeast Kluyveromyces marxianus A4 and A5 in BALB/c mice
Kefir yeast, Kluyveromyces marxianus, has been evaluated for its potential probiotic properties—survivability, non-pathogenicity, and antioxidant and anti-microbial activities. However, host gut microbiota modula...
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Article
Open AccessIdentification and phylogenetic analysis of Enterococcus isolates using MALDI-TOF MS and VITEK 2
The bacterial genus Enterococcus encompasses 38 species. Two of the most common species are E. faecalis and E. faecium. Recently, however, there has been an increase in clinical reports concerning less prevalent
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Article
Effect of air chambers on the compression wave propagating along a high-speed railway tunnel
An array of air chambers embedded on the tunnel track is numerically investigated for different configurations. The air chambers act as an in-tunnel countermeasure to alleviate non-linear steepening of compres...
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Article
A Combined In Vitro and In Vivo Assessment of the Safety of the Yeast Strains Kluyveromyces marxianus A4 and A5 Isolated from Korean Kefir
Kefir is a traditional fermented milk containing beneficial bacteria and yeasts. Despite Kluyveromyces marxianus, isolated from kefir, gaining increasing attention as a potential probiotic yeast owing to its biol...
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Article
Estimating Bed Shear Stress Distribution over Bottom of a Channel on the Moving Vessel
Shear stress is critical in the determination and estimation of bedload transport and morphological changes. Generally, the bed shear stress is estimated in fields using three-dimensional flow velocities acqui...
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Article
Open AccessInvestigating heterogeneous defects in single-crystalline WS2 via tip-enhanced Raman spectroscopy
Nanoscale defects in two-dimensional (2D) transition metal dichalcogenides (TMDs) alter their intrinsic optical and electronic properties, and such defects require investigation. Atomic-resolution techniques s...
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Article
Experimental investigation for multiresponse optimization in rotary ultrasonic side milling of quartz
Quartz is one of the highly demanded advanced ceramics and has been attracting increasing attention for industrial applications owing to its excellent properties. However, significant challenges are yet to be ...
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Article
Achieving optimal process design for minimizing porosity in additive manufacturing of Inconel 718 using a deep learning-based pore detection approach
Among metal additive manufacturing (AM) techniques, directed energy deposition (DED) has the advantage of being able to stack various materials, including difficult-to-cut materials such as Inconel 718. Howeve...
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Article
Open AccessComparative efficacy and safety of infliximab and vedolizumab therapy in patients with inflammatory bowel disease: a systematic review and meta-analysis
There are limited comparative data for infliximab and vedolizumab in inflammatory bowel disease patients.
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Article
Re-Routing Infliximab Therapy: Subcutaneous Infliximab Opens a Path Towards Greater Convenience and Clinical Benefit
Subcutaneous infliximab recently received approval for the treatment of various immune-mediated inflammatory diseases in Europe, following pivotal clinical trials in patients with rheumatoid arthritis and infl...
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Article
Open AccessPerspectives on Subcutaneous Infliximab for Rheumatic Diseases and Inflammatory Bowel Disease: Before, During, and After the COVID-19 Era
The coronavirus disease 2019 (COVID-19) pandemic has prompted significant changes in patient care in rheumatology and gastroenterology, with clinical guidance issued to manage ongoing therapy while minimising ...
