6 Result(s)

Article

Author Correction: Guidelines and definitions for research on epithelial–mesenchymal transition

**g Yang, Parker Antin, Geert Berx… in Nature Reviews Molecular Cell Biology (2021)

Article

Guidelines and definitions for research on epithelial–mesenchymal transition

Epithelial–mesenchymal transition (EMT) encompasses dynamic changes in cellular organization from epithelial to mesenchymal phenotypes, which leads to functional changes in cell migration and invasion. EMT occ...

**g Yang, Parker Antin, Geert Berx… in Nature Reviews Molecular Cell Biology (2020)

Article

CRISPR/Cas9 Targets Chicken Embryonic Somatic Cells In Vitro and In Vivo and generates Phenotypic Abnormalities

Chickens are an invaluable model for studying human diseases, physiology and especially development, but have lagged in genetic applications. With the advent of Programmable Engineered Nucleases, genetic manip...

Kwaku Dad Abu-Bonsrah, Dongcheng Zhang, Donald F. Newgreen in Scientific Reports (2016)

Article

Direct repression of MYB by ZEB1 suppresses proliferation and epithelial gene expression during epithelial-to-mesenchymal transition of breast cancer cells

Epithelial-to-mesenchymal transition (EMT) promotes cell migration and is important in metastasis. Cellular proliferation is often downregulated during EMT, and the reverse transition (MET) in metastases appea...

Honor J Hugo, Lloyd Pereira, Randy Suryadinata, Yvette Drabsch… in Breast Cancer Research (2013)

Article

Staurosporine augments EGF-mediated EMT in PMC42-LA cells through actin depolymerisation, focal contact size reduction and Snail1 induction – A model for cross-modulation

A feature of epithelial to mesenchymal transition (EMT) relevant to tumour dissemination is the reorganization of actin cytoskeleton/focal contacts, influencing cellular ECM adherence and motility. This is cou...

Honor J Hugo, Razan Wafai, Tony Blick, Erik W Thompson, Donald F Newgreen in BMC Cancer (2009)

Article

Induction of epithelial to mesenchymal transition in PMC42-LA human breast carcinoma cells by carcinoma-associated fibroblast secreted factors

Breast carcinoma is accompanied by changes in the acellular and cellular components of the microenvironment, the latter typified by a switch from fibroblasts to myofibroblasts.

Stephanie C Lebret, Donald F Newgreen, Erik W Thompson… in Breast Cancer Research (2007)