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  1. No Access

    Protocol

    Correlated Single-Molecule Magnetic Tweezers and Fluorescence Measurements of DNA-Enzyme Interactions

    Combining force spectroscopy and fluorescence microscopy provides a substantial improvement to the single-molecule toolbox by allowing simultaneous manipulation and orthogonal characterizations of the conforma...

    Julene Madariaga-Marcos, Pierre Aldag, Dominik J. Kauert… in Single Molecule Analysis (2024)

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    Article

    The energy landscape for R-loop formation by the CRISPR–Cas Cascade complex

    Clustered regularly interspaced short palindromic repeats (CRISPR) sequences and CRISPR-associated (Cas) genes comprise CIRSPR-Cas effector complexes, which have revolutionized gene editing with their ability ...

    Dominik J. Kauert, Julene Madariaga-Marcos… in Nature Structural & Molecular Biology (2023)