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  1. Article

    Open Access

    Sensitive detection of human papillomavirus type 16 E7-specific T cells by ELISPOT after multiple in vitro stimulations of CD8+ T cells with peptide-pulsed autologous dendritic cells

    Cervical cancer is the second most common gynecological cancer amongst women world-wide. Despite optimized protocols, standard treatments still face several disadvantages. Therefore, research aims at the devel...

    Nathalie Cools, Peter Ponsaerts, Marc Lenjou, Griet Nijs… in Molecular Cancer (2006)

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    Article

    Apoptosis: mechanisms and relevance in cancer

    Apoptosis or programmed cell death is a process with typical morphological characteristics including plasma membrane blebbing, cell shrinkage, chromatin condensation and fragmentation. A family of cystein-depe...

    Katrien Vermeulen, Dirk R. Van Bockstaele, Zwi N. Berneman in Annals of Hematology (2005)

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    Article

    Mean corpuscular hemoglobin is not increased in Fmr1 knockout mice

    A slight increase in mean corpuscular hemoglobin (MCH) has been reported in erythrocytes from human fragile X patients. As it is difficult to perform casecontrolled studies in patients with fragile X syndrome,...

    Edwin Reyniers, Dirk R. Van Bockstaele, Kristel De Boulle, R. Frank Kooy… in Human Genetics (1996)

  4. No Access

    Article

    Cimetidine induced pancytopenia

    We describe a 26 year-old male with a pancytopenia possibly due to cimetidine. Using progenitor cell culture techniques we investigated the mechanism of this bone marrow toxicity. Our results show a cimetidine...

    Wim Uyttenbroeck, Marcel Korthout, Robrecht De Bock, Dirk R. Van Bockstaele… in Blut (1990)