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Epigenetic programming underpins B cell dysfunction in human SLE

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  1. Article

    Open Access

    Antibody-secreting cell destiny emerges during the initial stages of B-cell activation

    Upon stimulation, B cells assume heterogeneous cell fates, with only a fraction differentiating into antibody-secreting cells (ASC). Here we investigate B cell fate programming and heterogeneity during ASC dif...

    Christopher D. Scharer, Dillon G. Patterson, Tian Mi in Nature Communications (2020)

  2. Article

    Open Access

    Human snoRNA-93 is processed into a microRNA-like RNA that promotes breast cancer cell invasion

    Genetic searches for tumor suppressors have recently linked small nucleolar RNA misregulations with tumorigenesis. In addition to their classically defined functions, several small nucleolar RNAs are now known...

    Dillon G. Patterson, Justin T. Roberts, Valeria M. King in npj Breast Cancer (2017)