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  1. No Access

    Article

    Calreticulin exposure dictates the immunogenicity of cancer cell death

    Anthracyclin-treated tumor cells are particularly effective in eliciting an anticancer immune response, whereas other DNA-damaging agents such as etoposide and mitomycin C do not induce immunogenic cell death....

    Michel Obeid, Antoine Tesniere, François Ghiringhelli, Gian Maria Fimia… in Nature Medicine (2007)

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    Article

    A novel dendritic cell subset involved in tumor immunosurveillance

    The interferon (IFN)-γ–induced TRAIL effector mechanism is a vital component of cancer immunosurveillance by natural killer (NK) cells in mice1,2. Here we show that the main source of IFN-γ is not the conventiona...

    Julien Taieb, Nathalie Chaput, Cédric Ménard, Lionel Apetoh… in Nature Medicine (2006)

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    Article

    Wild-type p53 induced sensitization of mutant p53 TNF-resistant cells: Role of caspase-8 and mitochondria

    In the present study, we have investigated the mechanisms by which the restoration of wild-type (wt) p53 functions in p53 mutant cells increases their susceptibility to the cytotoxic action of tumor necrosis fact...

    Maya Ameyar-Zazoua, Nathanaël Larochette, Guillaume Dorothée… in Cancer Gene Therapy (2002)