Skip to main content

7 Result(s)

within Didier Métivier Remove this filter

and

  1. No Access

    Protocol

    Cytofluorometric Purification of Diploid and Tetraploid Cancer Cells

    During malignant transformation, cells can increase their ploidy and hence become polyploid (mostly tetraploid). Frequently, however, tetraploid cells undergo asymmetric divisions, in turn entailing a reductio...

    Maria Castedo, Lorenzo Galluzzi, Ilio Vitale, Laura Senovilla… in Cell Cycle Synchronization (2011)

  2. No Access

    Article

    Calreticulin exposure dictates the immunogenicity of cancer cell death

    Anthracyclin-treated tumor cells are particularly effective in eliciting an anticancer immune response, whereas other DNA-damaging agents such as etoposide and mitomycin C do not induce immunogenic cell death....

    Michel Obeid, Antoine Tesniere, François Ghiringhelli, Gian Maria Fimia… in Nature Medicine (2007)

  3. No Access

    Article

    A novel dendritic cell subset involved in tumor immunosurveillance

    The interferon (IFN)-γ–induced TRAIL effector mechanism is a vital component of cancer immunosurveillance by natural killer (NK) cells in mice1,2. Here we show that the main source of IFN-γ is not the conventiona...

    Julien Taieb, Nathalie Chaput, Cédric Ménard, Lionel Apetoh… in Nature Medicine (2006)

  4. No Access

    Article

    Chemosensitization by erythropoietin through inhibition of the NF-κB rescue pathway

    Two cell lines that exemplify erythropoietin (EPO) receptor-positive tumors, human renal carcinoma cell lines RCC and the myelomonocytic leukemia cell line U937, were investigated for the apoptosis-modulatory ...

    Gabrielle Carvalho, Carmen Lefaucheur, Claire Cherbonnier, Didier Métivier… in Oncogene (2005)

  5. No Access

    Article

    Dynamic evolution of the adenine nucleotide translocase interactome during chemotherapy-induced apoptosis

    The mitochondrial permeability transition pore complex (PTPC) is involved in the control of the mitochondrial membrane permeabilization during apoptosis, necrosis and autophagy. Indeed, the adenine nucleotide ...

    Florence Verrier, Aurélien Deniaud, Morgane LeBras, Didier Métivier… in Oncogene (2004)

  6. No Access

    Article

    Wild-type p53 induced sensitization of mutant p53 TNF-resistant cells: Role of caspase-8 and mitochondria

    In the present study, we have investigated the mechanisms by which the restoration of wild-type (wt) p53 functions in p53 mutant cells increases their susceptibility to the cytotoxic action of tumor necrosis fact...

    Maya Ameyar-Zazoua, Nathanaël Larochette, Guillaume Dorothée… in Cancer Gene Therapy (2002)

  7. No Access

    Article

    Adenine nucleotide translocator mediates the mitochondrial membrane permeabilization induced by lonidamine, arsenite and CD437

    An increasing number of experimental chemotherapeutic agents induce apoptosis by directly triggering mitochondrial membrane permeabilization (MMP). Here we examined MMP induced by lonidamine, arsenite, and the...

    Anne-Sophie Belzacq, Chahrazed El Hamel, Helena L A Vieira, Isabel Cohen… in Oncogene (2001)