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Article
Open AccessShared decision making, prospektive Lebensqualität und das beste Interesse des Kindes: ethische Herausforderungen im Kontext von Behandlungsentscheidungen bei Frühgeborenen an der Grenze der Lebensfähigkeit
Behandlungsentscheidungen bei Frühgeburten an der Grenze der Lebensfähigkeit stellen eine große Herausforderung dar. In der Neonatologie hat sich das Konzept einer prognostischen Grauzone etabliert, die als ei...
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Article
Fears of compassion scales in psychosis: confirmatory factor analysis and psychometric properties
Previous research has supported the emergence of approaches focused on the cultivation of compassion as a means of decreasing psychopathology and improving well-being. However, some individuals show resistance...
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Chapter and Conference Paper
3D Animation to Address Pandemic Challenges: A Project-Based Learning Methodology
The use of 3D animations in medical education is becoming increasingly popular. Indeed, animations are an efficient way to present complex information, reducing time spent reading textbooks. Thus, in the educa...
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Chapter and Conference Paper
Systematic Literature Review of the Use of Virtual Reality in the Inclusion of Children with Autism Spectrum Disorders (ASD)
Virtual reality (VR) technologies have been evolving in recent decades, allowing simulating real-life situations in controlled and safe virtual environments, where they reveal increasingly realistic details. T...
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Chapter and Conference Paper
My Buddy: A 3D Game for Children Based on Voice Commands
Mobile devices, as smartphones and tablets, have presented an exponential growth, being part of our everyday life, particularly considering children [1]. Their daily habits are undoubtedly influenced by technolog...
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Chapter and Conference Paper
Towards an Accessibility Evaluation of eLearning Tools in Emerging 3D Virtual Environments Like Metaverse: Taking Advantage of Acquired Knowledge in Moodle and Second Life
Second Life (SL), a widely used Three-Dimensional Virtual World (3DVW), is being used as a tool for eLearning because of its interaction capabilities. On the other hand, accessibility is growing as a requireme...
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Chapter and Conference Paper
Automated Evaluation Tools for Web and Mobile Accessibility: A Systematic Literature Review
This research aims at investigating which web accessibility and usability tools, with the focus on the ones that warrant automation, are available to assess the quality of interfaces for people with disabiliti...
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Chapter and Conference Paper
Multisensory Experience for People with Hearing Loss: A Preliminary Study Using Haptic Interfaces to Sense Music
In this paper, we describe a preliminary study on a multisensory music experience for people with hearing loss. Our main goal is to provide a music event through visual and tactile stimuli, granting a multisen...
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Chapter and Conference Paper
BCI: Technologies and Applications Review and Toolkit Proposal
A typical example of a Brain-Computer Interface (BCI) is a system that allows a person to move a ball displayed on a computer screen to the left or to the right, simply by imagining the movement of the left or...
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Chapter and Conference Paper
Develo** an Application for Teaching Mathematics to Children with Dyscalculia: A Pilot Case Study
Dyscalculia is a specific neurological affliction that disrupts a person’s ability to understand and manipulate numbers. We intend to develop a serious game for children who attend primary school (up to 4th gr...
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Chapter
From Taken for Granted to Taken Seriously: The Linked Lives Life Course Principle Under Literature Analysis
The life course principle of linked lives, emphasising the interdependent nature of lives, is under-explored and taken for granted. Yet, it constitutes an independent contribution to the Life Course and Sociology...
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Chapter and Conference Paper
Effectiveness of Coach Marks or Instructional Overlay in Smartphone Apps Interfaces
Some mobile applications present a level of complexity with respect to the functionalities of the graphical interface that are not easily understood by all users in a first approach. The use of instructional o...
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Article
Open AccessALK2 inhibitors display beneficial effects in preclinical models of ACVR1 mutant diffuse intrinsic pontine glioma
Diffuse intrinsic pontine glioma (DIPG) is a lethal childhood brainstem tumour, with a quarter of patients harbouring somatic mutations in ACVR1, encoding the serine/threonine kinase ALK2. Despite being an amenab...
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Article
Correction to: International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma
There are two errors and one omission in the original article. Author Gottardo’s correct name is Nicholas G. Gottardo, author Hulleman’s correct affiliation is no. 3 (VUMC, Amsterdam), and the Acknowledgements...
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Article
International experience in the development of patient-derived xenograft models of diffuse intrinsic pontine glioma
Diffuse intrinsic pontine glioma is the most aggressive form of high grade glioma in children with no effective therapies. There have been no improvements in survival in part due poor understanding of underlyi...
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Article
Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells
The failure to develop effective therapies for pediatric glioblastoma (pGBM) and diffuse intrinsic pontine glioma (DIPG) is in part due to their intrinsic heterogeneity. We aimed to quantitatively assess the e...
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Article
Performance evaluation of different age groups for gestural interaction: a case study with Microsoft Kinect and Leap Motion
With the thriving of different natural interaction paradigms—such as gesture-based interfaces—it becomes important to understand how these novel interfaces can influence users’ performance when it comes to the...
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Article
Safe use of infliximab for the treatment of severe perianal Crohn’s disease after diagnosis and treatment of lymphoma
Inflammatory bowel disease is associated with an increased likelihood of develo** lymphoma. However, it is still controversial if this risk may be attributed to the disease itself or rather represents an eff...
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Article
Open AccessThe ten-year evolutionary trajectory of a highly recurrent paediatric high grade neuroepithelial tumour with MN1:BEND2 fusion
Astroblastomas are rare brain tumours which predominate in children and young adults, and have a controversial claim as a distinct entity, with no established WHO grade. Reports suggest a better outcome than h...
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Article
Usability evaluation of navigation tasks by people with intellectual disabilities: a Google and SAPO comparative study regarding different interaction modalities
This paper presents a case study regarding the usability evaluation of navigation tasks by people with intellectual disabilities. The aim was to investigate the factors affecting usability, by comparing their ...
