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1,658 Result(s)
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Article
The role of central neck dissection and adjuvant treatment in pT4aN0 laryngeal carcinoma treated with open partial horizontal laryngectomy
The study aimed to identify parameters that could predict oncological and functional outcomes in patients with pT4aN0 laryngeal squamous cell carcinoma (LSCC) who underwent open partial horizontal laryngectomy...
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AChR-seropositive myasthenia gravis in muscular dystrophy: diagnostic pitfalls and clinical management challenges
The co-occurrence of genetic myopathies with myasthenia gravis (MG) is extremely rare, however a few studies have been reported. We aim to explore the link between genetically inherited muscle disorders and im...
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Open AccessComorbidity in myasthenia gravis: multicentric, hospital-based, and controlled study of 178 Italian patients
Myasthenia gravis (MG) is an autoimmune disorder with fluctuating weakness that causes significant disability and morbidity. Comorbidities may influence the course of MG, particularly in specific subgroups. Th...
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Open AccessPersistent COVID-19 parosmia and olfactory loss post olfactory training: randomized clinical trial comparing central and peripheral-acting therapeutics
Although COVID-19 anosmia is often transient, patients with persistent olfactory dysfunction (pOD) can experience refractory parosmia and diminished smell. This study evaluated four putative therapies for paro...
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Article
Febrile infection-related epilepsy syndrome with claustrum lesion: an underdiagnosed inflammatory encephalopathy
To summarize the clinical characteristics and prognosis of febrile infection-related epilepsy syndrome with claustrum lesions (FIRES-C).
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Article
Botulinum neurotoxin as early treatment in acute-onset lesional hemiballism
Hemiballism (HB) and hemichorea (HC) are the most frequent secondary movement disorders, usually caused by cerebrovascular diseases. In only a minority of cases, these involuntary movements are not self-limite...
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Overnight switch from carbamazepine to eslicarbazepine in a real-life clinical scenario: a retrospective study
Carbamazepine (CBZ) is a first-choice anti-seizure medication (ASM) whose efficacy is often invalidated by adverse effects (AEs). Eslicarbazepine (ESL) is a structural derivative of CBZ with better pharmacokin...
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Praise of the clinical method in Neurology: a case of “person in the barrel” syndrome due to traumatic cervical injury
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Article
Jugular foramen stenosis in external hydrocephalus in infants
To measure the size of jugular foramina in infants affected by external hydrocephalus (EH) and in a control group, to support the hypothesis that a jugular foramen (JF) stenosis may determine dural venous sinu...
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Article
Clinical features, disease progression, and nuclear imaging in ATXN2-related parkinsonism in a longitudinal cohort
Spinocerebellar ataxia 2 (SCA2) with a low range of CAG repeat expansion of ATXN2 gene can present with predominant or isolated parkinsonism that closely resembles Parkinson’s disease (PD). This study is aimed at...
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Article
Posterolateral approaches to the thoracic spine for calcific disc herniation: is wider exposure always better?
To compare the costotransversectomy (CTV) and transpedicular (TP) approaches versus the transfacet (TF) approach for the surgical treatment of calcific thoracic spine herniations (cTDH), in terms of surgical a...
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Article
Phantom limb syndrome: from pathogenesis to treatment. A narrative review
Phantom Limb Syndrome (PLS) can be defined as the disabling or painful sensation of the presence of a body part that is no longer present after its amputation. Anatomical changes involved in Phantom Limb Syndr...
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Article
Bariatric surgery and dimethyl fumarate-induced lymphopenia in patients with multiple sclerosis
Lymphopenia is a known side effect of dimethyl fumarate (DMF), a disease-modifying therapy (DMT) for patients with multiple sclerosis (pwMS). A body mass index ≥ 30 kg/m2 has been identified as a protective facto...
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Article
Open AccessMidterm follow-up after embolization of intracranial aneurysms proximal to the circle of Willis with the Silk Vista flow diverter: the I-MAMA registry
The aim of this registry was to assess technical success, procedural safety and mid- to long-term follow-up results of the Silk Vista “Mama” (SVM) flow diverter (BALT, Montmorency, France) for the treatment of...
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Article
Influence of cognition on the correlation between objective and subjective upper limb measures in people with multiple sclerosis
A comprehensive assessment of upper limb (UL) function is mandatory in people with multiple sclerosis (PwMS), and the use of multiple objective and subjective measures is advisable. Findings on the role of cog...
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Article
Metabolic stroke-like events in a girl with pyruvate dehydrogenase complex deficiency caused by a novel de novo mutation in PDHA1
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Article
A novel quantitative method to evaluate lumbar disc degeneration: MRI histogram analysis
This study aimed to use MRI histogram analysis to routine MRI sequences to evaluate lumbar disc degeneration (LDD), illustrate the correlation between this novel method and the traditional Pfirrmann classifica...
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Article
Image-guided biopsy of intracranial lesions in children, with a small robotic device: a case series
Robot-assisted biopsies have gained popularity in the last years. Most robotic procedures are performed with a floor-based robotic arm. Recently, Medtronic Stealth Autoguide, a miniaturized robotic arm that wo...
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Is blood pTau a reliable indicator of the CSF status? A narrative review
The identification of biomarkers for the early diagnosis of Alzheimer’s disease (AD) is a crucial goal of the current research. Blood biomarkers are less invasive, easier to obtain and achievable by a cheaper ...
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Article
Open AccessMigraine chronification as an allostatic disorder: a proof-of-concept study
The underpinning biologics of migraine chronification are not well understood. We aim to investigate the role of the cumulative burden of stress, namely the allostatic load, in migraine chronification.