1,044 Result(s)
-
Article
Open AccessGender differences in clinical and biochemical parameters among patients hospitalized for schizophrenia: towards precision medicine
The scientific literature shows some gender differences in the clinical course of schizophrenia. The aim of this study is to identify gender differences in clinical and biochemical parameters in subjects affec...
-
Article
The correlation between cumulative burden of mental disorders and self-harm, shame, and insight in young female patients with schizophrenia
This study delves into the correlation between the cumulative burden of mental disorders and self-harm, shame, and insight in young female patients with schizophrenia. A prospective randomized controlled study...
-
Article
Open AccessThe impact of REM sleep loss on human brain connectivity
Brain function is vulnerable to the consequences of inadequate sleep, an adverse trend that is increasingly prevalent. The REM sleep phase has been implicated in coordinating various brain structures and is hy...
-
Article
Seizures in autoimmune-associated epilepsy: a long-term video-EEG monitoring study
-
Article
Open AccessAmyotrophic lateral sclerosis stratification: unveiling patterns with virome, inflammation, and metabolism molecules
Amyotrophic lateral sclerosis (ALS) is an untreatable and clinically heterogeneous condition primarily affecting motor neurons. The ongoing quest for reliable biomarkers that mirror the disease status and prog...
-
Article
The chronic use of serotonin norepinephrine reuptake inhibitors facilitates dyskinesia priming in early Parkinson’s disease
Parkinson’s disease (PD) patients are frequently exposed to antidepressant medications (ADMs). Norepinephrine (NE) and serotonin (5HT) systems have a role in levodopa-induced dyskinesias (LID) pathophysiology.
-
Article
Open AccessChatGPT vs. neurologists: a cross-sectional study investigating preference, satisfaction ratings and perceived empathy in responses among people living with multiple sclerosis
ChatGPT is an open-source natural language processing software that replies to users’ queries. We conducted a cross-sectional study to assess people living with Multiple Sclerosis’ (PwMS) preferences, satisfac...
-
Article
Jugular foramen stenosis in external hydrocephalus in infants
To measure the size of jugular foramina in infants affected by external hydrocephalus (EH) and in a control group, to support the hypothesis that a jugular foramen (JF) stenosis may determine dural venous sinu...
-
Article
History of traumatic brain injury is associated with increased grey-matter loss in patients with mild cognitive impairment
To investigate whether a history of traumatic brain injury (TBI) is associated with greater long-term grey-matter loss in patients with mild cognitive impairment (MCI).
-
Article
Open AccessDiagnostic value of regional homogeneity and fractional amplitude of low-frequency fluctuations in the classification of schizophrenia and bipolar disorders
Schizophrenia (SCZ) and bipolar disorders (BD) show significant neurobiological and clinical overlap. In this study, we wanted to identify indexes of intrinsic brain activity that could differentiate these dis...
-
Article
Open AccessCross-ancestry genetic investigation of schizophrenia, cannabis use disorder, and tobacco smoking
Individuals with schizophrenia frequently experience co-occurring substance use, including tobacco smoking and heavy cannabis use, and substance use disorders. There is interest in understanding the extent to ...
-
Article
Clinical and genetic characteristics of 1672 cases of amyotrophic lateral sclerosis in China: a single-center retrospective study
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease. In recent years, continuous discoveries of new ALS-causing genes have enhanced the understanding of the genotype–phenotype relationship...
-
Article
Open AccessCDKL5 deficiency-related neurodevelopmental disorders: a multi-center cohort study in Italy
CDKL5 deficiency disorder (CDD) is a complex clinical condition resulting from non-functional or absent CDKL5 protein, a serine–threonine kinase pivotal for neural maturation and synaptogenesis. The disorder m...
-
Article
Open AccessMidterm follow-up after embolization of intracranial aneurysms proximal to the circle of Willis with the Silk Vista flow diverter: the I-MAMA registry
The aim of this registry was to assess technical success, procedural safety and mid- to long-term follow-up results of the Silk Vista “Mama” (SVM) flow diverter (BALT, Montmorency, France) for the treatment of...
-
Article
Image-guided biopsy of intracranial lesions in children, with a small robotic device: a case series
Robot-assisted biopsies have gained popularity in the last years. Most robotic procedures are performed with a floor-based robotic arm. Recently, Medtronic Stealth Autoguide, a miniaturized robotic arm that wo...
-
Article
Open AccessSex impacts treatment decisions in multiple sclerosis
Individual disease-modifying treatment (DMT) decisions might differ between female and male people with MS (pwMS).
-
Article
Open AccessOne-year efficacy of a lifestyle behavioural intervention on physical and mental health in people with severe mental disorders: results from a randomized controlled trial
This multicentric randomized controlled trial (RCT), carried out in six Italian University mental health sites, aims to test the efficacy of a six-month psychosocial intervention (LYFESTYLE) on Body Mass Index...
-
Article
Risk of esketamine anesthesia on the emergence delirium in preschool children after minor surgery: a prospective observational clinical study
Emergence delirium (ED) is a common mental complication during recovery from anesthesia. However, studies on the effects of esketamine, an intravenous anesthetic for pediatrics, on ED are still lacking. This s...
-
Article
Open AccessEarly intensive versus escalation treatment in patients with relapsing–remitting multiple sclerosis in Austria
To compare the effectiveness of early intensive treatment (EIT) versus escalation treatment (ESC) in a nationwide observational cohort of almost 1000 people with relapsing–remitting multiple sclerosis (RRMS).
-
Article
Open AccessProgression independent of relapse activity in relapsing multiple sclerosis: impact and relationship with secondary progression
We investigated the occurrence and relative contribution of relapse-associated worsening (RAW) and progression independent of relapse activity (PIRA) to confirmed disability accrual (CDA) and transition to sec...
