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183 Result(s)
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Article
Open AccessThe effect of early postnatal auditory stimulation on outcomes in preterm infants
Preterm infants are deprived of in utero sensory stimulation during the third trimester, an important period of central nervous system development. As a result, maturational trajectories are often reduced in infa...
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Open AccessMonitoring Activity and Gait in Children (MAGIC) using digital health technologies
Digital health technologies (DHTs) can collect gait and physical activity in adults, but limited studies have validated these in children. This study compared gait and physical activity metrics collected using...
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Article
Maturation of cardioventilatory physiological trajectories in extremely preterm infants
In extremely preterm infants, persistence of cardioventilatory events is associated with long-term morbidity. Therefore, the objective was to characterize physiologic growth curves of apnea, periodic breathing...
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Article
Maternal periconceptional folic acid supplementation and risk for fetal congenital genitourinary system defects
Taking folic acid supplementation could reduce the risk of neural tube defects for offspring in the maternal periconceptional period, but the relationship between folic acid use and other birth defects remains...
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Article
Recombinant IGF-1/BP3 protects against intestinal injury in a neonatal mouse NEC model
Recombinant human IGF-1/binding protein-3 (rhIGF-1/BP3) is currently being tested in phase II clinical trials in premature infants to prevent bronchopulmonary dysplasia, but its impact on the neonatal intestin...
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Article
Open AccessReduction in regulatory T cells in preterm newborns is associated with necrotizing enterocolitis
Despite multifactorial pathogenesis, dysregulation of inflammatory immune response may play a crucial role in necrotizing enterocolitis (NEC). Regulatory T cells (Tregs) are involved in immune tolerance early ...
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Article
Hypoxemia events in preterm neonates are associated with urine oxidative biomarkers
Intermittent hypoxemia (IH) events are common in preterm neonates and are associated with adverse outcomes. Animal IH models can induce oxidative stress. We hypothesized that an association exists between IH a...
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Article
Plasma serotonergic biomarkers are associated with hypoxemia events in preterm neonates
Hypoxemia is a physiological manifestation of immature respiratory control in preterm neonates, which is likely impacted by neurotransmitter imbalances. We investigated relationships between plasma levels of t...
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Article
CT-based identification of pediatric non-Wilms tumors using convolutional neural networks at a single center
Deep learning (DL) is more and more widely used in children’s medical treatment. In this study, we have developed a computed tomography (CT)-based DL model for identifying undiagnosed non-Wilms tumors (nWTs) f...
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Article
Open AccessEuthyroid sick syndrome and its association with complications of type 1 diabetes mellitus onset
To evaluate (i) the prevalence and association of euthyroid sick syndrome (ESS) [decreased FT3 and/or FT4 and normal/decreased TSH] with severity indexes of type 1 diabetes mellitus (T1DM) onset such as diabet...
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Article
Open AccessConsequences of gestational diabetes mellitus on neonatal cardiovascular health: MySweetHeart Cohort study
Hyperglycaemic disorders of pregnancy are associated with offspring cardiovascular alterations.
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Article
Neurodevelopmental consequences of preterm punctate white matter lesions: a systematic review
To evaluate punctate white matter lesion (PWML) influence in preterm infants on the long-term neurodevelopmental outcome (NDO).
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Article
Antepartum periodontitis treatment and risk of offspring screening positive for autism spectrum disorder
To evaluate if treating maternal periodontal disease, a pro-inflammatory condition, during pregnancy (intervention) compared to after pregnancy (control) reduces the likelihood of offspring screening positive ...
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Article
Effect of age on human ACE2 and ACE2-expressing alveolar type II cells levels
Angiotensin-converting enzyme 2 (ACE2) is the receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which causes COVID-19. Viral entry requires ACE2 and transmembrane protease serine 2 (TMP...
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Chapter
Pump Therapy and Use of Technologies
Neonatal Diabetes Mellitus (NDM) treatment and clinical management still represent a strong challenge for pediatricians and diabetologists. Therefore, many authors have shown increasing interest in the use of ...
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Abuse, Human Trafficking, and Prostitution
Human trafficking and sexual exploitation have enormous health consequences. Abusive elements compose part of its definition. Sex work, under certain circumstances, poses a unique occupational challenge to hea...
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Etiology of Sexual Offending
To understand the act of sexual offending the considerations, research say, must start earlier in the life of the individual. A variety of factors and their interaction can set off a process as soon as in chil...
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Article
Short and long-term outcomes of children with autoimmune congenital heart block treated with a combined maternal-neonatal therapy. A comparison study
The short and long-term outcomes of children with anti-Ro/La-related congenital heart block treated with a combined maternal-neonatal therapy protocol were compared with those of controls treated with other th...
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Article
Evolution of congenital anomalies of urinary tract in children with and without solitary kidney
We hypothesized that children with congenital solitary functioning kidney (CSFK) present forms of congenital urinary tract anomalies (CUTA) with higher chance of spontaneous resolution compared with patients w...
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Article
Neuroimaging and neurodevelopmental outcome after early fetal growth restriction: NEUROPROJECT—FGR
Adverse neurodevelopmental outcomes and MRI alterations are reported in infants born after fetal growth restriction (FGR). This study evaluates the additional role of FGR over prematurity in determining brain ...