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  1. Article

    Open Access

    Antiretroviral drugs induce oxidative stress and neuronal damage in the central nervous system

    HIV-associated neurocognitive disorder (HAND), characterized by a wide spectrum of behavioral, cognitive, and motor dysfunctions, continues to affect approximately 50 % of HIV(+) patients despite the success o...

    Cagla Akay, Michael Cooper, Akinleye Odeleye, Brigid K. Jensen in Journal of NeuroVirology (2014)

  2. Article

    Open Access

    Soybean-derived Bowman-Birk inhibitor inhibits neurotoxicity of LPS-activated macrophages

    Lipopolysaccharide (LPS), the major component of the outer membrane of gram-negative bacteria, can activate immune cells including macrophages. Activation of macrophages in the central nervous system (CNS) con...

    Jieliang Li, Li Ye, Denise R Cook, Xu Wang, **** Liu in Journal of Neuroinflammation (2011)