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Article
Open AccessAntiretroviral drugs induce oxidative stress and neuronal damage in the central nervous system
HIV-associated neurocognitive disorder (HAND), characterized by a wide spectrum of behavioral, cognitive, and motor dysfunctions, continues to affect approximately 50 % of HIV(+) patients despite the success o...
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Article
Open AccessSoybean-derived Bowman-Birk inhibitor inhibits neurotoxicity of LPS-activated macrophages
Lipopolysaccharide (LPS), the major component of the outer membrane of gram-negative bacteria, can activate immune cells including macrophages. Activation of macrophages in the central nervous system (CNS) con...