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Metabolomic and genetic architecture of gestational diabetes subtypes

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  1. Article

    Open Access

    Higher maternal adiposity reduces offspring birthweight if associated with a metabolically favourable profile

    Higher maternal BMI during pregnancy is associated with higher offspring birthweight, but it is not known whether this is solely the result of adverse metabolic consequences of higher maternal adiposity, such ...

    William D. Thompson, Robin N. Beaumont, Alan Kuang, Nicole M. Warrington in Diabetologia (2021)

  2. Article

    Correction to: Hyperglycemia and Adverse Pregnancy Outcome Follow-Up Study: newborn anthropometrics and childhood glucose metabolism

    A Correction to this paper has been published: https://doi.org/10.1007/s00125-021-05421-7

    Monica E. Bianco, Alan Kuang, Jami L. Josefson, Patrick M. Catalano in Diabetologia (2021)

  3. Article

    Hyperglycemia and Adverse Pregnancy Outcome Follow-Up Study: newborn anthropometrics and childhood glucose metabolism

    We aimed to examine associations of newborn anthropometric measures with childhood glucose metabolism with the hypothesis that greater newborn birthweight, adiposity and cord C-peptide are associated with high...

    Monica E. Bianco, Alan Kuang, Jami L. Josefson, Patrick M. Catalano in Diabetologia (2021)

  4. Article

    Metabolomic and genetic associations with insulin resistance in pregnancy

    Our study aimed to integrate maternal metabolic and genetic data related to insulin sensitivity during pregnancy to provide novel insights into mechanisms underlying pregnancy-induced insulin resistance.

    Yu Liu, Alan Kuang, Octavious Talbot, James R. Bain, Michael J. Muehlbauer in Diabetologia (2020)

  5. Article

    Maternal glucose levels during pregnancy and childhood adiposity in the Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study

    Maternal type 2 diabetes during pregnancy and gestational diabetes are associated with childhood adiposity; however, associations of lower maternal glucose levels during pregnancy with childhood adiposity, ind...

    William L. Lowe Jr, Lynn P. Lowe, Alan Kuang, Patrick M. Catalano in Diabetologia (2019)

  6. Article

    Maternal metabolites during pregnancy are associated with newborn outcomes and hyperinsulinaemia across ancestries

    We aimed to determine the association of maternal metabolites with newborn adiposity and hyperinsulinaemia in a multi-ethnic cohort of mother–newborn dyads.

    Rachel Kadakia, Michael Nodzenski, Octavious Talbot, Alan Kuang in Diabetologia (2019)

  7. Article

    Associations of maternal BMI and insulin resistance with the maternal metabolome and newborn outcomes

    Maternal obesity increases the risk for large-for-gestational-age birth and excess newborn adiposity, which are associated with adverse long-term metabolic outcomes in offspring, probably due to effects mediat...

    Victoria Sandler, Anna C. Reisetter, James R. Bain, Michael J. Muehlbauer in Diabetologia (2017)