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    Article

    Can a Therapeutic Strategy for Hypotension Improve Cerebral Perfusion and Oxygenation in an Experimental Model of Hemorrhagic Shock and Severe Traumatic Brain Injury?

    Restoration of brain tissue perfusion is a determining factor in the neurological evolution of patients with traumatic brain injury (TBI) and hemorrhagic shock (HS). In a porcine model of HS without neurologic...

    Ana Paula de Carvalho Canela Balzi, Denise Aya Otsuki, Lucia Andrade in Neurocritical Care (2023)

  2. Article

    Open Access

    Terlipressin combined with conservative fluid management attenuates hemorrhagic shock-induced acute kidney injury in rats

    Hemorrhagic shock (HS), a major cause of trauma-related mortality, is mainly treated by crystalloid fluid administration, typically with lactated Ringer’s (LR). Despite beneficial hemodynamic effects, such as ...

    Leticia Urbano Cardoso Castro, Denise Aya Otsuki in Scientific Reports (2022)

  3. Article

    Open Access

    Predictors and their prognostic value for no ROSC and mortality after a non-cardiac surgery intraoperative cardiac arrest: a retrospective cohort study

    Data on predictors of intraoperative cardiac arrest (ICA) outcomes are scarce in the literature. This study analysed predictors of poor outcome and their prognostic value after an ICA. Clinical and laboratory ...

    Matheus F. Vane, Maria J. C. Carmona, Sergio M. Pereira, Karl B. Kern in Scientific Reports (2019)

  4. Article

    Open Access

    Effects of terlipressin as early treatment for protection of brain in a model of haemorrhagic shock

    We investigated whether treatment with terlipressin during recovery from hypotension due to haemorrhagic shock (HS) is effective in restoring cerebral perfusion pressure (CPP) and brain tissue markers of water...

    Keila Kazue Ida, Denise Aya Otsuki, Adolfo Toshiro Cotarelli Sasaki in Critical Care (2015)

  5. Article

    Open Access

    The effect of premedication with ketamine, alone or with diazepam, on anaesthesia with sevoflurane in parrots (Amazona aestiva)

    Premedication is rarely used in avian species. The aim of this study was to evaluate the effect of premedication on the quality of sevoflurane induction and anaesthesia in parrots. We hypothesised that premedi...

    Valéria Veras Paula, Denise Aya Otsuki in BMC Veterinary Research (2013)