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Crosstalk between small-cell lung cancer cells and astrocytes mimics brain development to promote brain metastasis

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    Open Access

    Radiotherapy in combination with CD47 blockade elicits a macrophage-mediated abscopal effect

    Radiation therapy is a mainstay of cancer treatment but does not always lead to complete tumor regression. Here we combine radiotherapy with blockade of the ‘don’t-eat-me’ cell-surface molecule CD47 in small c...

    Yoko Nishiga, Alexandros P. Drainas, Maya Baron, Debadrita Bhattacharya in Nature Cancer (2022)