4 Result(s)
within
Davide Prandi
Bioinformatics
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Article
A highly specific SpCas9 variant is identified by in vivo screening in yeast
Evolved SpCas9 variant evoCas9 has improved specificity and retains near wild-type on-target activity.
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Article
Open AccessErratum to: Unraveling the clonal hierarchy of somatic genomic aberrations
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Article
Open AccessUnraveling the clonal hierarchy of somatic genomic aberrations
Defining the chronology of molecular alterations may identify milestones in carcinogenesis. To unravel the temporal evolution of aberrations from clinical tumors, we developed CLONET, which upon estimation of ...
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Chapter and Conference Paper
A Formal Approach to Molecular Docking
Drugs are small molecules designed to regulate the activity of specific biological receptors. Design new drugs is long and expensive, because modifying the behavior of a receptor may have unpredicted side effe...
