6 Result(s)

Article

Author Correction: Allele specific repair of splicing mutations in cystic fibrosis through AsCas12a genome editing

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Giulia Maule, Antonio Casini, Claudia Montagna, Anabela S. Ramalho… in Nature Communications (2020)

Article

Allele specific repair of splicing mutations in cystic fibrosis through AsCas12a genome editing

Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the CFTR gene. The 3272–26A>G and 3849+10kbC>T CFTR mutations alter the correct splicing of the CFTR gene, generating new acceptor and...

Giulia Maule, Antonio Casini, Claudia Montagna, Anabela S. Ramalho… in Nature Communications (2019)

Article

Hit and go CAS9 delivered through a lentiviral based self-limiting circuit

In vivo application of the CRISPR-Cas9 technology is still limited by unwanted Cas9 genomic cleavages. Long-term expression of Cas9 increases the number of genomic loci non-specifically cleaved by the nuclease. H...

Gianluca Petris, Antonio Casini, Claudia Montagna… in Nature Communications (2017)

Article

An epidemiological investigation to reconstruct a probable human immunodeficiency virus -1 transmission network: a case report

Recently published studies have highlighted the importance of phylogenetic and phylodynamic analyses in supporting epidemiological investigations to reconstruct the transmission network of human immunodeficien...

Sara Serafino, Eleonora Cella, Claudia Montagna… in Journal of Medical Case Reports (2015)

Article

Antiretroviral treatment and expression of the mRNA levels for Pgp, MRP1, MRP4 and MRP5 in HIV antiretroviral naïve patients. Follow-up at 48 weeks

Francesca Falasca, Francesca Graziano, Laura Antonelli, Paola Maida… in Retrovirology (2010)