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A highly specific SpCas9 variant is identified by in vivo screening in yeast
Evolved SpCas9 variant evoCas9 has improved specificity and retains near wild-type on-target activity.
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Open AccessErratum to: Unraveling the clonal hierarchy of somatic genomic aberrations
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Open AccessUnraveling the clonal hierarchy of somatic genomic aberrations
Defining the chronology of molecular alterations may identify milestones in carcinogenesis. To unravel the temporal evolution of aberrations from clinical tumors, we developed CLONET, which upon estimation of ...