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    Article

    A highly specific SpCas9 variant is identified by in vivo screening in yeast

    Evolved SpCas9 variant evoCas9 has improved specificity and retains near wild-type on-target activity.

    Antonio Casini, Michele Olivieri, Gianluca Petris, Claudia Montagna in Nature Biotechnology (2018)

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    Open Access

    Erratum to: Unraveling the clonal hierarchy of somatic genomic aberrations

    Davide Prandi, Sylvan C. Baca, Alessandro Romanel in Genome Biology (2017)

  3. Article

    Open Access

    Unraveling the clonal hierarchy of somatic genomic aberrations

    Defining the chronology of molecular alterations may identify milestones in carcinogenesis. To unravel the temporal evolution of aberrations from clinical tumors, we developed CLONET, which upon estimation of ...

    Davide Prandi, Sylvan C Baca, Alessandro Romanel, Christopher E Barbieri in Genome Biology (2014)