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  1. No Access

    Article

    Effects of DL-3-n-Butylphthalide on Vascular Dementia and Angiogenesis

    3-n-Butylphthalide (NBP) is a compound extracted from Chinese celery and is used as an anti-hypertensive herbal medicine for treating stroke patients. The aim of this study is to demonstrate the effects and me...

    Lihong Zhang, Lanhai Lü, W. M. Chan, Yin Huang, Maria S. M. Wai… in Neurochemical Research (2012)

  2. No Access

    Article

    β-sitosterol inhibits high cholesterol-induced platelet β-amyloid release

    Recently, increasing evidence has linked high cholesterol to the pathogenesis of Alzheimer’s disease (AD), suggesting that cholesterol may be a target for develo** new compounds to prevent or treat AD. Plant...

    Chun Shi, Jun Liu, Fengming Wu, **aoMing Zhu… in Journal of Bioenergetics and Biomembranes (2011)

  3. No Access

    Article

    Bilobalide prevents apoptosis through activation of the PI3K/Akt pathway in SH-SY5Y cells

    Bilobalide, a sesquiterpene trilactone constituent of Ginkgo biloba leaf extracts, has been proposed to exert protective and trophic effects on neurons. However, mechanisms underlying the protective effects of bi...

    Chun Shi, Fengming Wu, David T. Yew, Jie Xu, Yonghong Zhu in Apoptosis (2010)

  4. No Access

    Article

    Effects of Gingko Extract (EGb761) on oxidative damage under different conditions of serum supply

    Standardized Ginkgo biloba extract EGb761 is known to have multivalent properties such as anti-oxidation and anti-apoptosis. In this study, we determined in rat pheochromocytoma (PC12) cells effects of EGb761 ...

    Chun Shi, Zhibing Yao, Jie Xu, David T. Yew in Journal of Bioenergetics and Biomembranes (2009)

  5. No Access

    Article

    Development of the human insular cortex: differentiation, proliferation, cell death, and appearance of 5HT-2A receptors

    The development of the human insula was studied in the foetuses from 21 to 32 gestation weeks, using silver staining, immunohistochemistry of proliferative cell nuclear antigen (PCNA), activated caspase-3, and...

    Maria S. M. Wai, Chun Shi, W. H. Kwong, Lihong Zhang… in Histochemistry and Cell Biology (2008)

  6. No Access

    Article

    Mitochondrial dysfunction in platelets and hippocampi of senescence-accelerated mice

    Senescence-accelerated mice (SAM) strains are useful models to understand the mechanisms of age-dependent degeneration. In this study, measurements of the mitochondrial membrane potential (Δψm) of platelets and t...

    Jie Xu, Chun Shi, Qi Li, Jiajia Wu… in Journal of Bioenergetics and Biomembranes (2007)