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    Article

    A left knee wound complication by non-Hodgkins lymphoma in bilateral total knee arthroplasties

    A 70-year-old woman with a history of bilateral primary knee osteoarthritis presented with a left knee wound complication, a non-Hodgkins lymphoma, after bilateral total knee arthroplasties. After exploring se...

    Mark S. Eskander, Erika McPhee in Archives of Orthopaedic and Trauma Surgery (2008)

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    Protocol

    Protein Detection Using Reversible Metal Chelate Stains

    Electrophoretically separated proteins may be visualized using organic dyes, such as Ponceau red, Amido black, fast green, or most commonly Coomassie Brilliant Blue (1,2). Alternatively, sensitive detection metho...

    Wayne F. Patton, Mark J. Lim, David Shepro in 2-D Proteome Analysis Protocols (1999)

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    Protocol

    Image Acquisition in 2-D Electrophoresis

    Prevalent methods for visualizing proteins resolved by two-dimensional (2-D) gel electrophoresis include autoradiography, silver staining, and Coomassie brilliant blue staining (1,2. The organic dye Coomassie bri...

    Wayne F. Patton, Mark J. Lim, David Shepro in 2-D Proteome Analysis Protocols (1999)

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    Article

    Thromboxane-induced neutrophil adhesion to pulmonary microvascular and aortic endothelium is regulated by CD18

    Thromboxane (Tx) A2 generation and subsequent selective pulmonary sequestration of neutrophils (PMNs) is characteristic of several forms of the adult respiratory distress syndrome (ARDS). Therefore, we examined P...

    Marc E. Wiles, Richard Welbourn, Gideon Goldman, Herbert B. Hechtman in Inflammation (1991)

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    Article

    Inflammatory agonists that increase microvascular permeability in vivo stimulate cultured pulmonary microvessel endothelial cell contraction

    Bovine pulmonary microvessel endothelial cells grown on a flexible substrate contract upon the addition of angiotensin II, thrombin, bradykinin, and U44069, a stable analogue of thromboxane A2. All these agents p...

    Nicole M. L. Morel, Palmina P. Petruzzo, Herbert B. Hechtman, David Shepro in Inflammation (1990)

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    Article

    Eicosanoid modulation of stress fibers in cultured bovine aortic endothelial cells

    Leukotrienes (LT) B4, LTD4, and thromboxanes (TX) are cytotoxic, and increase microvascular permeability. Because endothelial stress fibers are theorized to be part of the cytoskeletal mechanism by which microves...

    Seth L. Welles, David Shepro, Herbert B. Hechtman in Inflammation (1985)

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    Article

    Leukotriene induction of TxB2 in cultured bovine aortic endothelial cells

    The leukotrienes (LT) are potent mediators of inflammation, capable of inducing plasma leakage from postcapillary venules and vasoconstriction of terminal arterioles. Some microvascular effects may be attribut...

    Bernadette Dunham, David Shepro, Herbert B. Hechtman in Inflammation (1984)

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    Binding, internalization, and degradation of [125I]insulin by cultured bovine aortic endothelial cells: Effects of serotonin

    Cultured bovine aortic endothelial cells bind and internalize[125I]insulin and down regulate insulin receptors. Internalized insulin was not degraded significantly and diffused from the endothelial cells. Neither...

    Mary Pat Carson, Scott W. Peterson, Mary Ellen Moynahan, David Shepro in In Vitro (1983)

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    ADP is not Involved in Thrombin-induced Aggregation of Thrombocytes of a Non-mammalian Vertebrate

    PLATELETS are aggregated in vivo and in vitro by ADP1,2. Several agents such as thrombin, collagen and certain fatty acids cause aggregation by releasing ADP3. We reported that ADP, 5-hydroxytryptamine and adrena...

    FRANK A. BELAMARICH, DAVID SHEPRO, MARJA KIEN in Nature (1968)

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    Article

    In vitro Studies of Aggregation of Non-mammalian Thrombocytes

    NON-MAMMALIAN thrombocytes are nucleated cells which have been shown to have a haemostatic function paralleling that of mammalian platelets. Thrombocytes are active in the promotion of clots1 and clot retraction2

    FRANK A. BELAMARICH, MARGARET H. FUSARI, DAVID SHEPRO, MARJA KIEN in Nature (1966)