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  1. Article

    Open Access

    Hedgehog signaling activation induces stem cell proliferation and hormone release in the adult pituitary gland

    Hedgehog (HH) signaling is known to be essential during the embryonal development of the pituitary gland but the knowledge about its role in the adult pituitary and in associated tumors is sparse. In this repo...

    Joanna Pyczek, Rolf Buslei, David Schult, Annett Hölsken in Scientific Reports (2016)

  2. Article

    Open Access

    EZH2 is highly expressed in pituitary adenomas and associated with proliferation

    Enhancer of zeste homolog 2 (EZH2) is a core epigenetic regulator, playing a crucial role in cell cycle regulation. The protein is known to be associated with proliferation and worse outcome in several tumor e...

    David Schult, Annett Hölsken, Sonja Siegel, Michael Buchfelder in Scientific Reports (2015)