5 Result(s)

Article

Human brucellosis: recent advances and future challenges

David O’Callaghan in Infectious Diseases of Poverty (2020)

Article

Brucellosis in China: history, progress and challenge

Brucellosis is a neglected zoonosis. It causes acute febrile illness and a potentially debilitating chronic infection in humans, and livestock infection has substantial socioeconomic impact. Over the past two ...

Hai Jiang, David O’Callaghan, Jia-Bo Ding in Infectious Diseases of Poverty (2020)

Article

Methylnaltrexone for the treatment of opioid-induced constipation and gastrointestinal stasis in intensive care patients. Results from the MOTION trial

Constipation can be a significant problem in critically unwell patients, associated with detrimental outcomes. Opioids are thought to contribute to the mechanism of bowel dysfunction. We tested if methylnaltre...

Parind B. Patel, Stephen J. Brett, David O’Callaghan… in Intensive Care Medicine (2020)

Article

The Brucella TIR domain containing proteins BtpA and BtpB have a structural WxxxE motif important for protection against microtubule depolymerisation

The TIR domain-containing proteins BtpA/Btp1/TcpB and BtpB are translocated into host cells by the facultative intracellular bacterial pathogen Brucella. Here, they interfere with Toll like receptor signalling to...

Christine Felix, Burcu Kaplan Türköz, Sebastien Ranaldi… in Cell Communication and Signaling (2014)

Chapter and Conference Paper

Heterogeneous Grid Computing: Issues and Early Benchmarks

A heterogeneous implementation of the current LCG2/EGEE grid computing software is supported in the Grid-Ireland infrastructure. The porting and testing of the current software version of LCG2 is presented for...

Eamonn Kenny, Brian Coghlan, George Tsouloupas… in Computational Science – ICCS 2005 (2005)