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Article
Open AccessAssociation between P-pulmonale and respiratory morbidity in COPD: a secondary analysis of the BLOCK-COPD trial
Pulmonary hypertension (PH) in COPD confers increased risk of exacerbations (ECOPD). Electrocardiogram (ECG) indicators of PH are prognostic both in PH and COPD. In the Beta-Blockers for the Prevention of Acut...
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Article
Open AccessBilirubin-associated single nucleotide polymorphism (SNP) and respiratory health outcomes: a mendelian randomization study
Observational studies have shown an association between higher bilirubin levels and improved respiratory health outcomes. Targeting higher bilirubin levels has been proposed as a novel therapeutic strategy in ...
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Article
Open AccessPneumoproteins and biomarkers of inflammation and coagulation do not predict rapid lung function decline in people living with HIV
Chronic obstructive pulmonary disease (COPD) is among the leading causes of death worldwide and HIV is an independent risk factor for the development of COPD. However, the etiology of this increased risk and m...
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Article
Open AccessSerum bilirubin and chronic obstructive pulmonary disease (COPD): a systematic review
Bilirubin is a potent antioxidant and higher serum bilirubin levels have been associated with improved COPD outcomes. We performed a systematic review to evaluate the association between serum bilirubin levels...
