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Open AccessCompetitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells
Circulating monocytes can compete for virtually any tissue macrophage niche and become long-lived replacements that are phenotypically indistinguishable from their embryonic counterparts. As the factors regula...
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Article
Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signaling
The cytokine transforming growth factor-β (TGF-β) regulates the development and homeostasis of several tissue-resident macrophage populations, including microglia. TGF-β is not critical for microglia survival but...
