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Article
Open AccessPerceived patient burden and acceptability of MRI in comparison to PSA and ultrasound: results from the IP1-PROSTAGRAM study
The IP1-PROSTAGRAM study showed that a short, non-contrast MRI detected more significant cancers with similar rates of biopsy compared to PSA. Herein, we compare the expected and perceived burden of PSA, MRI a...
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Article
Landmarks in the evolution of prostate biopsy
Approaches and techniques used for diagnostic prostate biopsy have undergone considerable evolution over the past few decades: from the original finger-guided techniques to the latest MRI-directed strategies, ...
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Article
Open AccessAdjusting for verification bias in diagnostic accuracy measures when comparing multiple screening tests - an application to the IP1-PROSTAGRAM study
Novel screening tests used to detect a target condition are compared against either a reference standard or other existing screening methods. However, as it is not always possible to apply the reference standa...
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Article
Focal therapy compared to radical prostatectomy for non-metastatic prostate cancer: a propensity score-matched study
Focal therapy (FT) ablates areas of prostate cancer rather than treating the whole gland. We compared oncological outcomes of FT to radical prostatectomy (RP).
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Article
Rethinking prostate cancer screening: could MRI be an alternative screening test?
In the past decade rigorous debate has taken place about population-based screening for prostate cancer. Although screening by serum PSA levels can reduce prostate cancer-specific mortality, it is unclear whet...
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Article
Open AccessUse of Imaging to Optimise Prostate Cancer Tumour Volume Assessment for Focal Therapy Planning
Rapid advances in imaging of the prostate have facilitated the development of focal therapy and provided a non-invasive method of estimating tumour volume. Focal therapy relies on an accurate estimate of tumou...
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Article
Open AccessA prospective analysis of robotic targeted MRI-US fusion prostate biopsy using the centroid targeting approach
Robotic prostate biopsy is an emerging technology. Recent development of this tool has allowed the performance of a transperineal prostate biopsy allowing pre-programmed standardized biopsy schemes. Prospectiv...
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Article
Diagnostic value of MRI-based PSA density in predicting transperineal sector-guided prostate biopsy outcomes
Prostate-specific antigen (PSA) density (PSAD) has potential to increase the diagnostic utility of PSA, yet has had poor uptake in clinical practice. We aimed to determine the diagnostic value of magnetic reso...
