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Article
Open AccessUnited States house dust Pb concentrations are influenced by soil, paint, and house age: insights from a national survey
Lead (Pb) in house dust contributes significantly to blood lead levels (BLLs) in children which may result in dire health consequences. Assessment of house dust Pb in the United States, relationships with Pb i...
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Article
Examination of Ethical Decision-Making Models Across Disciplines: Common Elements and Application to the Field of Behavior Analysis
Human service practitioners from varying fields make ethical decisions daily. At some point during their careers, many behavior analysts may face ethical decisions outside the range of their previous education...
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Article
A national survey of lead and other metal(loids) in residential drinking water in the United States
Exposure to lead (Pb), arsenic (As) and copper (Cu) may cause significant health issues including harmful neurological effects, cancer or organ damage. Determination of human exposure-relevant concentrations o...
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Article
Fatigue and functional outcomes in cancer rehabilitation
Cancer-related fatigue (CRF) is one of the most common symptoms experienced by oncology patients, though its impact on functional outcomes during inpatient rehabilitation is relatively unknown. The purpose of ...
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Article
Open AccessGastrointestinal Tolerability of Once-Weekly Dulaglutide 3.0 mg and 4.5 mg: A Post Hoc Analysis of the Incidence and Prevalence of Nausea, Vomiting, and Diarrhea in AWARD-11
Gastrointestinal (GI) events are the most frequent treatment-emergent adverse events (TEAEs) reported for glucagon-like peptide-1 receptor agonist therapies. This post hoc analysis of the AWARD-11 phase 3 tri...
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Article
Open AccessAnalysis of the StoRM cohort reveals physical activity to be associated with survival in metastatic breast cancer
Benefits of physical activity are widely demonstrated for early stage cancers but few studies have focused on metastatic disease. The purpose of this study was to determine the impact of physical activity on s...
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Article
A neural network trained for prediction mimics diverse features of biological neurons and perception
Recent work has shown that convolutional neural networks (CNNs) trained on image recognition tasks can serve as valuable models for predicting neural responses in primate visual cortex. However, these models t...
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Article
Open Access64-Channel Carbon Fiber Electrode Arrays for Chronic Electrophysiology
A chief goal in neuroscience is to understand how neuronal activity relates to behavior, perception, and cognition. However, monitoring neuronal activity over long periods of time is technically challenging, a...
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Article
A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer
The breast cancer risk variants identified in genome-wide association studies explain only a small fraction of the familial relative risk, and the genes responsible for these associations remain largely unknow...
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Article
Open AccessScreening for comorbid conditions in patients enrolled in the SODA registry: a 2-year observational analysis
This 2-year analysis assessed frequency of comorbidities and comorbidity screening in the Somatuline® (lanreotide, LAN) Depot for Acromegaly (SODA) registry.
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Chapter and Conference Paper
Conditional Infilling GANs for Data Augmentation in Mammogram Classification
Deep learning approaches to breast cancer detection in mammograms have recently shown promising results. However, such models are constrained by the limited size of publicly available mammography datasets, in ...
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Chapter
The Tree of Participation: Our Thoughts About Growing a Culture of Participation Between Young People, Parents and Health Team Staff
This chapter is written by a group of young people, parent carers and health service staff and is about our experiences of participating in and contributing towa...
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Article
A multicenter, observational study of lanreotide depot/autogel (LAN) in patients with acromegaly in the United States: 2-year experience from the SODA registry
This analysis evaluates the 2-year effectiveness and safety of lanreotide depot/autogel (LAN), as well as treatment convenience and acromegaly symptom relief, from the Somatuline® Depot for Acromegaly (SODA) regi...
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Article
Open AccessCorrection: Corrigendum: Engineering and optimising deaminase fusions for genome editing
Nature Communications 7: Article number: 13330 (2016); Published 2 November 2016; Updated 9 October 2017. The original version of this Article contained an error in the email address of the corresponding autho...
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Article
Open AccessTreatment adherence and persistence with long-acting somatostatin analog therapy for the treatment of acromegaly: a retrospective analysis
Many patients with acromegaly require medical treatment that includes somatostatin analogs (SSAs). Long-acting SSA formulations are widely used, due in part to increased patient convenience and increased treat...
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Article
Diversity and evolution of class 2 CRISPR–Cas systems
CRISPR–Cas systems form two major classes that differ in the organization of their effector modules. The effector modules of class 2 systems consist of a singl...
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Chapter and Conference Paper
A Multi-scale CNN and Curriculum Learning Strategy for Mammogram Classification
Screening mammography is an important front-line tool for the early detection of breast cancer, and some 39 million exams are conducted each year in the United States alone. Here, we describe a multi-scale con...
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Chapter
Religion, the Spiritual Dimension and Social Development
This chapter will suggest that religion has had a positive influence on social development over the centuries and could have, and should have, a much greater contribution in the current context. It will furthe...
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Chapter and Conference Paper
\(\upmu \) Proxy: A Hardware Relay for Anonymous and Secure Internet Access
Privacy and anonymity on the Internet have become a serious concern. Even when anonymity tools like Tor or VPNs are used, the IP and therefore the approximate geolocation from which the user connects to such a...
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Article
Open AccessEngineering and optimising deaminase fusions for genome editing
Precise editing is essential for biomedical research and gene therapy. Yet, homology-directed genome modification is limited by the requirements for genomic lesions, homology donors and the endogenous DNA repa...
