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within Science, Humanities and Social Sciences, multidisciplinary Remove this filter Science, Humanities and Social Sciences, multidisciplinary Remove this filter Science, multidisciplinary Remove this filter Darran P. O’Connor Remove this filter

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  1. Article

    Open Access

    Integration of genomic, transcriptomic and proteomic data identifies two biologically distinct subtypes of invasive lobular breast cancer

    Invasive lobular carcinoma (ILC) is the second most frequently occurring histological breast cancer subtype after invasive ductal carcinoma (IDC), accounting for around 10% of all breast cancers. The molecular...

    Magali Michaut, Suet-Feung Chin, Ian Majewski, Tesa M. Severson… in Scientific Reports (2016)

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  2. Article

    Open Access

    Copy number load predicts outcome of metastatic colorectal cancer patients receiving bevacizumab combination therapy

    Increased copy number alterations (CNAs) indicative of chromosomal instability (CIN) have been associated with poor cancer outcome. Here, we study CNAs as potential biomarkers of bevacizumab (BVZ) response in ...

    Dominiek Smeets, Ian S. Miller, Darran P. O’Connor, Sudipto Das… in Nature Communications (2018)

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