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  1. No Access

    Article

    Combination Therapy with KRAS and P38α siRNA Suppresses Colorectal Cancer Growth and Development in SW480 Cell Line

    Colorectal cancer (CRC) is one of the most prevalence malignancies in a different society with a high rate of death. The KRAS and p38α axes have critical roles in the development, migration, and growth of nume...

    Shiva Kamran, Ensiyeh Seyedrezazadeh… in Journal of Gastrointestinal Cancer (2022)

  2. No Access

    Article

    Expression profiles of miR-196, miR-132, miR-146a, and miR-134 in human colorectal cancer tissues in accordance with their clinical significance

    Colorectal cancer (CRC) is among the most widespread malignancies in the world. MicroRNA (miRNA) has been identified as an important modulator of the biological processes of the cells. This group of noncoding ...

    Mahafarin Maralani, Dariush Shanehbandi, Milad Asadi… in Wiener klinische Wochenschrift (2021)

  3. No Access

    Article

    Anticancer Impacts of Terminalia catappa Extract on SW480 Colorectal Neoplasm Cell Line

    Colorectal cancer (CRC) is one of the most lethal and prevalent cancers throughout the world. Despite the remarkable advance in the field, drug resistance still remains as an unresolved problem in cancer. Henc...

    Dariush Shanehbandi, Habib Zarredar, Milad Asadi… in Journal of Gastrointestinal Cancer (2021)

  4. No Access

    Article

    Overexpression and Clinicopathological Correlation of Long Noncoding RNA TMPO-AS1 in Colorectal Cancer Patients

    Long noncoding RNA (lncRNA) has been identified as an important modulator of gene expression and other activities of the cells. This kind of genes also has a significant role in the growth and development of h...

    Haniye Mohammadrezakhani, Behzad Baradaran… in Journal of Gastrointestinal Cancer (2020)

  5. No Access

    Article

    Evaluation of the Methylation of MIR129-2 Gene in Gastric Cancer

    Genetic and epigenetic changes have strong role in the development of gastric cancer. The mutation of the MIR129-2 gene is one of the major causes in many cancers, especially gastric cancer. The aim of this study...

    Nazila Alizadeh, Milad Asadi, Dariush Shanehbandi… in Journal of Gastrointestinal Cancer (2020)

  6. No Access

    Article

    Transcript Level of MicroRNA Processing Elements in Gastric Cancer

    Aberrant expression of microRNAs (miRNAs) has been implicated in the etiopathogenesis and development of various cancers. Drosha and Dicer are the main components of the miRNA biosynthesis machine. Another enz...

    Milad Asadi, Dariush Shanehbandi, Venus Zafari… in Journal of Gastrointestinal Cancer (2019)

  7. No Access

    Article

    Expression Level of miR-34a in Tumor Tissue from Patients with Esophageal Squamous Cell Carcinoma

    miR-34a has been shown to be involved in P53 regulation. In this study, we aimed to evaluate the expression level of miR-34a in esophageal cancer and compare it with that of the normal marginal tissues.

    Milad Asadi, Dariush Shanehbandi, Hanieh Mohammadpour… in Journal of Gastrointestinal Cancer (2019)

  8. No Access

    Article

    siRNA-Mediated Silencing of HMGA2 Induces Apoptosis and Cell Cycle Arrest in Human Colorectal Carcinoma

    Overexpression of HMGA2, known as small non-histone chromosomal protein, is associated with progression of various tumors, including colorectal cancers. The aim of this study was to investigate the effect of a...

    Sahar Esmailzadeh, Behzad Mansoori, Ali Mohammadi… in Journal of Gastrointestinal Cancer (2017)