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Article
MR-guided prostate SBRT in prostate cancer patients with low-volume metastatic disease
Recent data have found an overall survival benefit from prostate-directed radiotherapy in patients with low-volume metastatic prostate cancer. Prostate SBRT is an attractive treatment in this setting and may b...
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Article
Breast cancer subtype and intracranial recurrence patterns after brain-directed radiation for brain metastases
Brain metastases from breast cancer are frequently managed with brain-directed radiation but the impact of subtype on intracranial recurrence patterns after radiation has not been well-described. We investigat...
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Article
Local control after brain-directed radiation in patients with cystic versus solid brain metastases
Brain metastases can be radiographically cystic or solid. Cystic metastases are associated with a greater intracranial disease burden and poorer oncologic outcomes, but the impact of cystic versus solid appear...
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Chapter
SRS and SBRT Integration with Supportive Care
Advanced techniques in radiotherapy including stereotactic radiotherapy (both intracranial and SBRT) hold significant promise in the treatment of patients with metastatic cancer, both by allowing dose escalati...
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Article
The emerging role of stereotactic radiotherapy in gastrointestinal malignancies: a review of the literature and analysis from the Irish perspective
Primary and secondary malignancies of the liver and pancreas result in significant morbidity and mortality, with increasing incidence and increasing demands on health services worldwide. Surgery is the only cu...
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Article
Open AccessHeterogeneity in high-risk prostate cancer treated with high-dose radiation therapy and androgen deprivation therapy
Our aim was to assess the heterogeneity of high-risk (HR) prostate cancer managed with high-dose external beam radiotherapy (EBRT) with androgen deprivation therapy (ADT).
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Article
Erratum to: Rapid progression of intracranial melanoma metastases controlled with combined BRAF/MEK inhibition after discontinuation of therapy: a clinical challenge
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Article
Rapid progression of intracranial melanoma metastases controlled with combined BRAF/MEK inhibition after discontinuation of therapy: a clinical challenge
Novel systemic therapies with anti-tumor activity in the brain including small molecules targeting BRAF and MEK, and immune checkpoint inhibition, offer the possibility of improved control of intracranial dise...
