![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Open AccessEvidence of natural selection in the mitochondrial-derived peptides humanin and SHLP6
Mitochondrial-derived peptides are encoded by mitochondrial DNA but have biological activity outside mitochondria. Eight of these are encoded by sequences within the mitochondrial 12S and 16S ribosomal genes: ...
-
Article
Complex structure of the activating immunoreceptor NKG2D and its MHC class I–like ligand MICA
The major histocompatibility complex (MHC) class I homolog, MICA, is a stress-inducible ligand for NKG2D, a C-type lectin–like activating immunoreceptor. The crystal structure of this ligand-receptor complex t...
-
Article
Interactions of human NKG2D with its ligands MICA, MICB, and homologs of the mouse RAE-1 protein family
NKG2D is an activating receptor that is expressed on most natural killer (NK) cells, CD8 αβ T cells, and γδ T cells. Among its ligands is the distant major histocompatibility complex class I homolog MICA, whi...