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Article
Molecular definition of the endogenous Toll-like receptor signalling pathways
Innate immune pattern recognition receptors, such as the Toll-like receptors (TLRs), are key mediators of the immune response to infection and central to our understanding of health and disease1. After microbial ...
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Article
Open AccessThe Gb3-enriched CD59/flotillin plasma membrane domain regulates host cell invasion by Pseudomonas aeruginosa
The opportunistic pathogen Pseudomonas aeruginosa has gained precedence over the years due to its ability to develop resistance to existing antibiotics, thereby necessitating alternative strategies to understand ...
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Protocol
Image-Based Quantitation of Host Cell–Toxoplasma gondii Interplay Using HRMAn: A Host Response to Microbe Analysis Pipeline
Research on Toxoplasma gondii and its interplay with the host is often performed using fluorescence microscopy-based imaging experiments combined with manual quantification of acquired images. We present here an ...
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Chapter
A 72-Month Clinical Experience with the ST. JUDE MEDICAL® Cardiac Valve Prosthesis at Newark Beth Israel Medical Center
The clinical experience with the ST. JUDE MEDICAL® cardiac valve prosthesis at the Newark Beth Israel Medical Center has recently been reviewed. This institution was one of the original investigational centers fo...