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Article
Early Literature on Adolescent Social Media Use, Substance Use, and Depressive Symptoms During the COVID-19 Pandemic: A Sco** Review
The COVID-19 pandemic led to unprecedented changes in daily life that impacted health among all populations, including adolescents. We conducted a sco** review of early literature (through June 20, 2021) on ...
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Open AccessPlacental transcriptomic signatures of prenatal and preconceptional maternal stress
Prenatal exposure to maternal psychological stress is associated with increased risk for adverse birth and child health outcomes. Accumulating evidence suggests that preconceptional maternal stress may also be...
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Article
Relationships Between Recent Adverse Childhood Experiences (ACEs) and Somatic Symptoms in Adolescence
Early identification and interventions are imperative for mitigating the harmful effects of adverse childhood experiences (ACEs). Nonetheless, a substantial barrier persists in identifying adolescents experien...
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Article
Open AccessGender-based violence in the context of armed conflict in Northern Ethiopia
Gender-based violence (GBV) particularly against women is unfortunately common during armed conflicts. No rigorous and comprehensive empirical work has documented the extent of GBV and its consequences that to...
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Article
Effectiveness of a care bundle for primary prevention of intraventricular hemorrhage in high-risk neonates: a Bayesian analysis
To determine whether an intraventricular hemorrhage (IVH) prevention bundle featuring midline-elevated positioning reduced IVH among high-risk infants.
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Article
Open AccessShort Report: Circulating microRNAs are associated with incident diabetes over 10 years in Japanese Americans
Epigenetic changes precede the development of diabetes by many years, providing clues to its pathogenesis. We explored whether the epigenetic markers, circulating microRNAs (miRNAs), were associated with incid...
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Article
Open AccessMaternal sedentary behavior during pre-pregnancy and early pregnancy and mean offspring birth size: a cohort study
Sedentary behavior is associated with adverse health outcomes in the general population. Whether sedentary behavior during pregnancy is associated with newborn outcomes, such as birth size, is not established,...
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Article
Transgenerational Transmission of Preterm Birth Risk: The Role of Race and Generational Socio-Economic Neighborhood Context
Objectives We investigated associations of mothers’ preterm birth (PTB) status with her infants’ PTB risk. We also examined whether this relationship differs by mothers’ race and generati...
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Article
Maternal Birthplace is Associated with Low Birth Weight Within Racial/Ethnic Groups
Introduction While disparities in low birth weight (LBW) incidence by racial/ethnic group are well known, differences in LBW incidence by maternal birthplace within racial/ethnic groups, ...
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Article
Birth Weight and Birth Weight for Gestational Age in Relation to Risk of Hospitalization with Primary Hypertension in Children and Young Adults
Introduction Low birth weight has been associated with an increased risk of hypertension in children. Less clear is whether high birth weight is also associated with risk. We evaluated ov...
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Article
Construct validity and factor structure of the Pittsburgh Sleep Quality Index among pregnant women in a Pacific-Northwest cohort
Poor sleep quality during pregnancy is associated with adverse obstetric and neuropsychiatric outcomes. Despite its routine use as a sleep quality assessment scale among men and non-pregnant women, the psychom...
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Article
A Longitudinal Study of Changes in Prenatal Care Utilization Between First and Second Births and Low Birth Weight
Because previous analyses of prenatal care (PNC) utilization and risk of low birth weight (LBW) may have been influenced by selection bias, we conducted a study using longitudinal data of women with repeat pre...
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Associations of Early and Late Gestational Weight Gain with Infant Birth Size
Associations of gestational weight gain (GWG) during specific periods of pregnancy with infant birth size have been inconsistent. Infant sex-specific differences in these associations are unknown
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Article
Open AccessThe transcriptional landscape of age in human peripheral blood
Disease incidences increase with age, but the molecular characteristics of ageing that lead to increased disease susceptibility remain inadequately understood. Here we perform a whole-blood gene expression met...
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Open AccessPlacental mitochondrial DNA content and placental abruption: a pilot study
Mitochondrial biogenesis and adequate energy production are important for embryogenesis and placentation. Previous studies documented alterations in maternal blood mitochondrial DNA (mtDNA) copy number—a marke...
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Article
Is the fetoplacental ratio a differential marker of fetal growth restriction in small for gestational age infants?
Higher placental weight relative to birthweight has been described as an adaptive mechanism to fetal hypoxia in small for gestational age (SGA) infants. However, placental weight alone may not be a good marke...
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Article
Open AccessSleep duration, vital exhaustion, and odds of spontaneous preterm birth: a case–control study
Preterm birth is a leading cause of perinatal morbidity and mortality worldwide, resulting in a pressing need to identify risk factors leading to effective interventions. Limited evidence suggests potential re...
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Article
Open AccessSleep duration and plasma leptin concentrations in early pregnancy among lean and overweight/obese women: a cross sectional study
Early-pregnancy short sleep duration is predictive of gestational diabetes and preeclampsia; mechanisms for these associations are unknown. Leptin, an adipocyte-derived peptide involved in regulating food inta...
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Open AccessAgreement of self-reported physician diagnosis of migraine with international classification of headache disorders-II migraine diagnostic criteria in a cross-sectional study of pregnant women
Migraine, a common chronic-intermittent disorder among reproductive age women, has emerged as a novel risk factor for adverse perinatal outcomes. Diagnostic reliability of self-report of physician-diagnosed mi...
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Article
Systematic identification of trans eQTLs as putative drivers of known disease associations
Lude Franke and colleagues report the results of a large expression QTL study performed on peripheral blood samples from 5,311 individuals. They identify trans-eQTL effects for 103 independent loci that were prev...