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  1. No Access

    Article

    Siglec-6 is a target for chimeric antigen receptor T-cell treatment of chronic lymphocytic leukemia

    The only current curative treatment for chronic lymphocytic leukemia (CLL) is allogenic hematopoietic stem cell transplantation. Chimeric antigen receptor treatment targeting CD19 for CLL achieved some complet...

    Damian Kovalovsky, Jeong Heon Yoon, Matthew G. Cyr, Samantha Simon… in Leukemia (2021)

  2. Article

    Open Access

    Safety and clinical activity of PD-L1 blockade in patients with aggressive recurrent respiratory papillomatosis

    Recurrent respiratory papillomatosis (RRP) is a human papillomavirus (HPV)-driven disorder that causes substantial morbidity and can lead to fatal distal airway obstruction and post-obstructive pneumonias. Pat...

    Clint T. Allen, Sunmin Lee, Scott M. Norberg… in Journal for ImmunoTherapy of Cancer (2019)

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  3. Article

    Open Access

    PLZF play as an indirect facilitator of thymic retention for the innate-like T-cells to aquire innate-like functions

    **n Cao, **ao-xia Ma, Yu-jia Xue, Yan Zeng, **an-yu Zhang, Ying Lu… in Cell Death & Disease (2018)

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  4. No Access

    Article

    The BTB–zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions

    Invariant natural killer cells recognize glycolipids presented by CD1d molecules and can mediate rapid innate responses. Sant'Angelo and colleagues show that these cells express the transcription factor PLZF, ...

    Damian Kovalovsky, Olisambu U Uche, Sonia Eladad, Robin M Hobbs… in Nature Immunology (2008)