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  1. Article

    Open Access

    Identification of a pleiotropic locus on chromosome 7q for a composite left ventricular wall thickness factor and body mass index: the HyperGEN Study

    Left ventricular (LV) mass and wall thickness are closely associated with measures of body size and blood pressure and also correlated with systolic and diastolic function, suggesting a contribution of common ...

    Weihong Tang, Richard B Devereux, Na Li, Albert Oberman in BMC Medical Genetics (2009)

  2. Article

    Open Access

    The SGLT2 inhibitor dapagliflozin in heart failure with preserved ejection fraction: a multicenter randomized trial

    Patients with heart failure and preserved ejection fraction (HFpEF) have a high burden of symptoms and functional limitations, and have a poor quality of life. By targeting cardiometabolic abmormalities, sodiu...

    Michael E. Nassif, Sheryl L. Windsor, Barry A. Borlaug in Nature Medicine (2021)

  3. Article

    Open Access

    Semaglutide in HFpEF across obesity class and by body weight reduction: a prespecified analysis of the STEP-HFpEF trial

    In the STEP-HFpEF trial, semaglutide improved symptoms, physical limitations and exercise function and reduced body weight in patients with obesity phenotype of heart failure and preserved ejection fraction (H...

    Barry A. Borlaug, Dalane W. Kitzman, Melanie J. Davies, Søren Rasmussen in Nature Medicine (2023)