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Article
Metabolic remodelling during early mouse embryo development
During early mammalian embryogenesis, changes in cell growth and proliferation depend on strict genetic and metabolic instructions. However, our understanding of metabolic reprogramming and its influence on ep...
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Article
Open AccessConstruction of intracellular asymmetry and asymmetric division in Escherichia coli
The design principle of establishing an intracellular protein gradient for asymmetric cell division is a long-standing fundamental question. While the major molecular players and their interactions have been e...
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Protocol
Isolation and Characterization of Methionine-Independent Clones from Methionine-Dependent Cancer Cells
Unlike normal cells, transformed cells are unable to grow when methionine in the growth media is restricted. Reversion to methionine independence is a rare event in transformed and malignant cells. Methionine-...
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Chapter
Light Emitting Diodes
In this chapter, the basics of the light emitting diodes are reviewed. Since its invention in the 20th century, the light emitting diode has evolved into a major life-changer for human being. Most of the focus...
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Article
Morphology and crystalline structure of inclusion compounds formed between poly(ethylene glycol) and urea
The poly(ethylene glycol) (PEG, with M w 2000)-urea inclusion compound (IC) crystallized at high temperature region showed two typical orientations, flat-on and edge-on crystals. 2D-XRD and polari...
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Article
Open AccessComputational identification of a transiently open L1/S3 pocket for reactivation of mutant p53
The tumour suppressor p53 is the most frequently mutated gene in human cancer. Reactivation of mutant p53 by small molecules is an exciting potential cancer therapy. Although several compounds restore wild-typ...
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Article
Improvement of the yield function of continuum mechanics of textured polycrystals
The calculation procedure of the continuum mechanics of textured polycrystals (CMTP) method is reviewed to estimate calculating time with various yield functions (YFs). A so-called semi-quadratic YF is propose...
