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Article
General-purpose DNA computation
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Article
Self-assembled amphiphilic NIR-II emissive nano-micelles for imaging-guided photothermal therapy of colorectal cancer
Colorectal cancer (CRC) is one of the major causes of cancer-related mortality worldwide. Most near-infrared (NIR) agents used in clinical CRC treatment are at NIR-I (700–900 nm) window, which has limitations ...
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Article
Open AccessA spatially localized DNA linear classifier for cancer diagnosis
Molecular computing is an emerging paradigm that plays an essential role in data storage, bio-computation, and clinical diagnosis with the future trends of more efficient computing scheme, higher modularity wi...
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Article
Covalent stabilization of DNA nanostructures on cell membranes for efficient surface receptor-mediated labeling and function regulations
One major challenge of using DNA nanostructures for cellular and in vivo applications is their insufficiently structural integrity that stems from the non-covalent base pairing and stacking in complex cellular an...
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Article
SMURF1, a promoter of tumor cell progression?
Overexpression of HECT-type E3 ubiquitin ligase SMURF1 is correlated with poor prognosis in patients with various cancers, such as glioblastoma, colon cancer, and clear cell renal cell carcinoma. SMURF1 acts a...
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Article
Nucleic Acids Analysis
Nucleic acids are natural biopolymers of nucleotides that store, encode, transmit and express genetic information, which play central roles in diverse cellular events and diseases in living things. The analysi...
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Article
Cancer diagnosis with DNA molecular computation
Early and precise cancer diagnosis substantially improves patient survival. Recent work has revealed that the levels of multiple microRNAs in serum are informative as biomarkers for the diagnosis of cancers. H...
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Article
DNA Nanotechnology on Live Cell Membranes
Recent developments in DNA nanotechnology have brought various nanoscale structures, devices and functional systems for different applications. As biological barriers with significant functions, cell membranes...
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Chapter and Conference Paper
Robust Crack Defect Detection in Inhomogeneously Textured Surface of Near Infrared Images
Robust crack defect detection in solar cells has been challenging because of the inhomogeneously textured surface, low contrast between crack defect and background, the diversity of crack types, and so on. To ...
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Article
DNA probes for monitoring dynamic and transient molecular encounters on live cell membranes
Cells interact with the extracellular environment through molecules expressed on the membrane. Disruption of these membrane-bound interactions (or encounters) can result in disease progression. Advances in sup...
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Article
Open AccessA Green Route for Substrate-Independent Oil-Repellent Coatings
Oil repellent surface have lots of practical applications in many fields. Current oil repellent coating may suffer from limited liquid repellency to oils or environmental risks. In this work, we report an eco-...
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Article
A cascade reaction network mimicking the basic functional steps of adaptive immune response
Biological systems use complex ‘information-processing cores’ composed of molecular networks to coordinate their external environment and internal states. An example of this is the acquired, or adaptive, immun...
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Article
Open AccessNuclease-resistant synthetic drug-DNA adducts: programmable drug-DNA conjugation for targeted anticancer drug delivery
Targeted drug delivery is poised to improve cancer therapy, for which synthetic DNA can serve as targeting ligands (for example, aptamers) or drug nanocarriers. Inspired by natural DNA adducts, we report synth...
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Chapter
Molecular Engineering to Enhance Aptamer Functionality
Rapid development of bioanalysis and biomedicine requires enhanced and multiple functionality of aptamers. The field of molecular engineering has advanced to a stage where more and more molecular functions can...
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Chapter
Functional Materials for Signal Amplification of Molecular Beacons
Rapid development of bioanalysis and biomedicine requires higher sensitivity and selectivity of MBs. Functional materials are generally characterized as those materials which possess particular native properti...
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Article
Open AccessA micro-nano porous oxide hybrid for efficient oxygen reduction in reduced-temperature solid oxide fuel cells
Tremendous efforts to develop high-efficiency reduced-temperature (≤ 600°C) solid oxide fuel cells are motivated by their potentials for reduced materials cost, less engineering challenge and better performanc...
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Article
Preparation and microstructure of glass-ceramics and ceramic composite materials
The technology and microstructure of glass-ceramics and ceramic composite materials were studied. A suitable ceramic body was chosen on the basis of the sintering temperature of CaO-Al2O3-SiO2 system glass-cerami...
