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Article
Correction: Midlife adiposity predicts earlier onset of Alzheimer’s dementia, neuropathology and presymptomatic cerebral amyloid accumulation
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Article
Midlife adiposity predicts earlier onset of Alzheimer’s dementia, neuropathology and presymptomatic cerebral amyloid accumulation
Understanding how midlife risk factors influence age at onset (AAO) of Alzheimer’s disease (AD) may provide clues to delay disease expression. Although midlife adiposity predicts increased incidence of AD, it ...
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Article
Open AccessNeurocognitive dysfunction and pharmacological intervention using guanfacine in a rhesus macaque model of self-injurious behavior
Self-injurious behavior (SIB) is a common comorbidity of psychiatric disorders but there is a dearth of information about neurological mechanisms underlying the behavior, and few animal models exist. SIB in hu...
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Chapter
Efficient Network Flow Based Min-Cut Balanced Partitioning
We consider the problem of bipartitioning a circuit into two balanced components that minimizes the number of crossing nets. Previously, Kernighan and Lin type (K&L) heuristics, simulated annealing approach, a...
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Article
VLSI Circuit Performance Optimization by Geometric Programming
Delay of VLSI circuit components can be controlled by varying their sizes. In other words, performance of VLSI circuits can be optimized by changing the sizes of the circuit components. In this paper, we defin...
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Article
The role of stilbenes in bleaching and colour stability of mechanical pulps. I. The reaction of lignin model stilbenes with alkali and oxygen
The reactions of lignin model hydroxystilbenes and TMP with alkaline hydrogen peroxide and with alkali and oxygen have been studied to determine the susceptibility of stilbenes, to oxidative degradation. Oxyge...
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Article
Probabilistic analysis of a grou** algorithm
We study thegrou** by swap** problem, which occurs in memory compaction and in computing the exponential of a matrix. In this problem we are given a sequence ofn numbers drawn from {0,1, 2,...,m−1} with repet...
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Chapter and Conference Paper
Strategies for In Vivo Quantification of Human Neuroreceptors by Positron Emission Tomography
At the present time, a number of groups of investigators are studying neuroreceptors and neurotransmitter systems with positron emission tomography (PET). In vivo quantification of neuroreceptors has been acco...
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Article
Floorplan design of VLSI circuits
In this paper we present two algorithms for the floorplan design problem. The algorithms are quite similar in spirit. They both use Polish expressions to represent floorplans and employ the search method of si...
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Book
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Chapter
Gate Matrix Layout
In this chapter, we consider the layout of MOS circuits in the style of Gate Matrix. This layout style was introduced by Lopez and Law [LoLa80] in 1980 for the layout of custom CMOS circuits. It is very simila...
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Chapter
PLA Folding
Programmable Logic Arrays (PLA’s) are structured logic arrays which implement multiple output combinational logic functions. They are perhaps the most popular circuit modules that implement two-level logic fun...
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Chapter
Array Optimization
In this chapter, we consider the problem of minimizing layout area of logic arrays. Most of the previous research efforts [DeSa83, HaNS82, WoLL87] on the subject have been concentrated on reducing layout area ...
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Chapter
Introduction
For many important practical or theoretical problems, the objective is to choose a “best” solution out of a large number of possible solutions. Such problems are typically known as combinatorial optimization prob...
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Chapter
Floorplan Design
Floorplan design [MaMH82, Otte82, LaDi85, PrCh85, WoWT86, WoLi86, WoLi87a] is the first stage of VLSI circuit layout. It is the problem of allocating spaces to a given set of circuit modules in the plane to mi...
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Chapter
Permutation Channel Routing
Most of the channel routing algorithms in the literature [Deut76, YoKu82, RiFi82, BuPe83, ReSS85] including the simulated annealing channel routers studied in Chapter 4 assume a model in which the pins on the ...
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Chapter
Placement
The general placement problem is the problem of placing a set of circuit modules on a chip such that a certain objective function is minimized. The ultimate goal is to minimize the total chip area occupied by ...
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Chapter
Channel Routing
The notion of channel routing was first introduced by Hashimoto and Stevens in 1971 [HaSt71]. Since then it has been used extensively in the layout of integrated circuits. This is an effective approach to the gen...
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Article
Artifacts in camera based single photon emission tomography due to time activity variation
Image quality in single photon emission computed tomography (SPECT) using a rotating gamma camera is dependent on the time course of the tracer in the field of view. If acquisition times are slow comapred to t...
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Article
Linear discriminant analysis of regional ejection fractions in the diagnosis of coronary artery disease
We studied the application of linear discriminant analysis to the computer assisted interpretation of rest and exercise gated blood pool studies. Data were obtained in 45 patients in whom the presence or absen...
