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    Article

    The impacts of the interaction of genetic variation, CYP11β2 and NEDD4L, with sodium intake on pediatric obesity with gender difference: a 3-year panel study

    This panel study was to predict the incidences of pediatric obesity by the interaction of sodium (Na) intake and nine single-nucleotide polymorphisms (SNPs) of salt-sensitive genes (SSGs), ACE(angiotensin-convert...

    M Lee, D Y Kwon, J Park in International Journal of Obesity (2017)

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    Article

    Conformational analysis of yvae peptide derivatives

    Active conformations of YVAE peptide derivatives that were competitive inhibitors of 3-hydroxy3-methylglutaryl–coenzyme A reductase (HMG–CoA reductase) were determined. A type I β-turn in N-terminuses of the s...

    V. V. Pak, D. Y. Kwon, L. M. Yun, A. Yili, H. A. Aisa in Chemistry of Natural Compounds (2012)

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    Chapter and Conference Paper

    Quantification of Bradykinesia Using Gyro-Sensors during Clinical Motor Examination in Idiopathic Parkinson’s Disease Patients

    The purpose of this study is to develop a quantitative measure of the bradykinesia which can be conveniently used during clinical motor examination (finger taps, forearm pronation/supination, foot-taps) in pat...

    J. W. Kim, Y. R. Kwon, G. M. Eom, D. Y. Kwon in 6th World Congress of Biomechanics (WCB 20… (2010)

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    Article

    Isolation and Identification of Peptides from Soy 11S-Globulin with Hypocholesterolemic Activity

    A peptide with hypocholesterolemic activity was isolated by HPLC from the pepsin hydrolysate of 11S-globulin. Its molecular weight (755.2 Da) and amino-acid sequence (Ile-Ala-Val-Pro-Gly-Glu-Val-Ala) were esta...

    V. V. Pak, M. S. Koo, T. D. Kasymova, D. Y. Kwon in Chemistry of Natural Compounds (2005)

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    Article

    Structure—Activity Relationships of the Peptide Ile-Ala-Val-Pro and Its Derivatives Revealed Using the Semi-Empirical AM1 Method

    Several peptides with hypocholesterinemic properties were investigated in order to reveal structure-activity relationships. The semi-empirical AM1 method and molecular dynamics were used to determine common st...

    V. V. Pak, M. Koo, N. Lee, M. S. Kim, D. Y. Kwon in Chemistry of Natural Compounds (2005)

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    Article

    Structures of the Peptide Leu-Pro-Tyr-Pro and Its Derivatives and the Nicotinamide Part of NADPH by a Semi-Empirical PM3 Method

    The capability of peptides Leu-Pro-Tyr-Pro (LPYP), Leu-Pro-Tyr-Pro-Arg (LPYPR), and Ser-Pro-Tyr-Pro-Arg (SPYPR) to occupy the part of the binding site ascribed to NADPH in the active center of 3-hydroxy-3-meth...

    V. V. Pak, M. Ku, N. Li, M. S. Kim, T. D. Kasymova in Chemistry of Natural Compounds (2005)

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    Article

    Conformation Analysis of Ile-Ala-Val-Pro Peptide and Its Derivatives by Circular Dichroism

    Ile-Ala-Val-Pro as a hypocholesterolemic peptide was isolated from soybean protein. We have synthesized four peptides, Ile-Ala-Val-Pro-Gly-Glu-Val-Ala, Leu-Ile-Ala-Val-Pro-Gly-Glu-Val-Ala, Ile-Ala-Val-Pro-Thr-...

    V. V. Pak, M. S. Koo, D. Y. Kwon, T. D. Kasimova in Chemistry of Natural Compounds (2004)

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    Article

    Cloning and sequence analyses of a 2,3-dihydroxybiphenyl 1,2-dioxygenase gene (bphC) from Comamonas sp. SMN4 for phylogenetic and structural analysis

    A genomic library of biphenyl-degrading Comamonas sp. SMN4 for isolating fragments containing the 2,3-dihydroxybiphenyl 1,2-dioxygenase (23DBDO) gene was constructed. The smallest subclone (pNPX9) encoding 23DBDO...

    N. R. Lee, D. Y. Kwon, K. H. Min in Journal of Industrial Microbiology and Biotechnology (2003)