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Article
Open AccessDoes a 6-point scale approach to post-treatment 18F-FDG PET-CT allow to improve response assessment in head and neck squamous cell carcinoma? A multicenter study
Response assessment to definitive non-surgical treatment for head and neck squamous cell carcinoma (HNSCC) is centered on the role of 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography ...
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Article
Successo terapeutico di Lenvatinib in seconda linea in un caso di carcinoma follicolare della tiroide avanzato
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Article
Mesolimbic dopaminergic dysfunction in Parkinson’s disease depression: evidence from a 123I-FP-CIT SPECT investigation
We investigated the striatal and extrastriatal DAT availability (SPM8) by [123I]FP-CIT-SPECT in 15 PD patients with depression and 35 PD patients without depression. A cluster with significant (p < 0.05) lower tr...
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Chapter
La gestione della dose in medicina nucleare
Le indagini diagnostiche di medicina nucleare si basano sulla somministrazione diretta al paziente di un radiofarmaco, ovvero una sostanza radioattiva che si distribuisce nei vari organi e tessuti sulla base d...
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Chapter
Elaborazioni tridimensionali in medicina nucleare
Come in radiologia, la visualizzazione di dati di tomografia computerizzata a emissione di fotone singolo (SPECT) e tomografia a emissione di positroni (PET) è tradizionalmente presentata come una serie di sez...
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Article
Brain perfusion effects of cholinesterase inhibitors in Parkinson’s disease with dementia
Several evidences suggest that cholinergic deficits may significantly contribute to dementia in Parkinson’s disease (PDD) and acetylcholinesterase inhibitors (ChEIs) have been reported to improve cognitive sym...
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Article
Presynaptic nigro-striatal function in a group of Alzheimer’s disease patients with parkinsonism: evidence from a dopamine transporter imaging study
The occurrence of parkinsonism in Alzheimer’s disease (AD) is quite common, however the molecular and neurochemical changes underlying such extrapyramidal features in AD have been not fully understood. Post-mo...
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Article
Dopaminergic degeneration and perfusional impairment in Lewy body dementia and Alzheimer’s disease
The clinical differentiation of Lewy body dementia (LBD) from Alzheimer’s disease (AD) may be difficult. The aim of the present study was to assess the dopamine transporter function and the perfusional pattern...
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Chapter and Conference Paper
Blood Flow Changes in Cerebral and Cerebellum Cortex in Obsessive-Compulsive Disorder Patients Evaluated with ECD-Tc99m SPET
A semiquantitative analysis of brain perfusion was assessed with 99mTc-ECD SPET in 30 pts affected by Obsessive-Compulsive Disorder (OCD) and in 8 normal controls. In OCD drug-free pts a significant blood flow in...
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Chapter and Conference Paper
Assessment of Brain Perfusion by ECD-Tc99m SPET IN RETT Syndrome
Rett syndrome (RS) is a progressive neurological pediatric disorder which affects only girls. The aim of our study is to determinate if brain perfusion abnormalities might be able to explain the clinical manif...
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Chapter
Hürthle Cell Tumor and Technetium-99m-Sestamibi Scintigraphy (Single Injection Double-Phase Study)
Single injection dual-phase MIBI thyroid scintigraphy was performed on 49 pts with a cold nodule on a previous Tc99m scintigraphy. In 8 pts the nodule displayed intense and persistent MIBI uptake (8 Hürthle ce...
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Chapter
Tc99m-ECD Brain SPET in Diagnosis of Cerebral Perfusion Abnormalities in Children with Therapy-Resistant Epilepsy
We performed Tc99m-ECD interictal SPET in 26 children with severe therapy-resistant epilepsy. All children underwent detailed clinical examination, EEG investigation and brain MRI. In 21/26 children, SPET demo...
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Article
Captopril radionuclide test in renovascular hypertension: a European multicentre study
The diagnostic work-up of renovascular hypertension is still controversial. The efficacy of renal scintigraphy with technetium-99m diethylene triamine penta-acetate (DTPA) before and after captopril (scintigra...
