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Chapter and Conference Paper
PAR-Based Architectural Pedagogy: A Case Study of Gridshell Design and Built Projects
This paper suggests a pedagogical strategy that roots in the notion of participatory action research (PAR). This methodology advocates a heuristic learning-by-doing process that hinges on recent computational ...
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Article
Open AccessPublisher Correction: Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer
The original version of this Article contained an error in Fig. 4. In the left histogram of the right panel of Fig. 4d, several data points were inadvertently deleted from the histogram during the production p...
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Article
Open AccessBarcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer
Primary triple negative breast cancers (TNBC) are prone to dissemination but sub-clonal relationships between tumors and resulting metastases are poorly understood. Here we use cellular barcoding of two treatm...
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Article
Regulation of PI3K signaling in T-cell acute lymphoblastic leukemia: a novel PTEN/Ikaros/miR-26b mechanism reveals a critical targetable role for PIK3CD
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematologic malignancy, and T-ALL patients are prone to early disease relapse and suffer from poor outcomes. The PTEN, PI3K/AKT and Notch pathways a...
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Article
The gene polymorphisms of IL-8(-251T/A) and IP-10(-1596C/T) are associated with susceptibility and progression of type 2 diabetic retinopathy in northern Chinese population
The aim of the present study is to investigate the association of the polymorphism of two genes in CXC chemokine family, interleukin-8 (IL-8) and interferon-inducible protein 10 (IP-10), with both susceptibili...
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Article
Open AccessFeasibility studies of time-like proton electromagnetic form factors at \(\overline{\rm P}\) ANDA at FAIR
Simulation results for future measurements of electromagnetic proton form factors at \(\overline{\rm P}\) ...
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Article
Rapamycin reduces severity of senile osteoporosis by activating osteocyte autophagy
Osteocyte is the orchestrator of bone remolding and decline in osteocyte autophagy is involved in senile osteoporosis. Our results suggested that rapamycin, at least in part by activating osteocyte autophagy, ...
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Article
Open AccessExperimental access to Transition Distribution Amplitudes with the P̄ANDA experiment at FAIR
Baryon-to-meson Transition Distribution Amplitudes (TDAs) encoding valuable new information on hadron structure appear as building blocks in the collinear factorized description for several types of hard exclu...
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Article
Open AccessCancer-derived immunoglobulin G promotes tumor cell growth and proliferation through inducing production of reactive oxygen species
Cancer cells have been found to express immunoglobulin G (IgG), but the exact functions and underlying mechanisms of cancer-derived IgG remain elusive. In this study, we first confirmed that downregulation of ...
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Article
Erratum to: Cerebral Scedosporium apiospermum infection presenting with intestinal manifestations
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Article
Cerebral Scedosporium apiospermum infection presenting with intestinal manifestations
We present a case of cerebral Scedosporium apiospermum infection presenting with intestinal manifestations in a 64-year-old male patient on immunosuppression for orthotopic liver transplantation. At admission, th...
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Article
The Large Observatory for X-ray Timing (LOFT)
High-time-resolution X-ray observations of compact objects provide direct access to strong-field gravity, to the equation of state of ultradense matter and to black hole masses and spins. A 10 m2-class instrument...
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Article
An auto-SCT-based total therapy resulted in encouraging outcomes in adolescents and young adults with acute lymphoblastic leukemia: report from a single center of China
Application of auto-SCT in the post-remission therapy for adolescents and young adults (AYAs) with ALL is controversial. We analyzed the outcomes of 79 AYAs (15–24 years) with ALL who received our designed tot...
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Article
Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder
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Article
Erratum: Genomewide association for schizophrenia in the CATIE study: results of stage 1
Correction to: Molecular Psychiatry (2008) 13, 570–584; doi: 10.1038/mp.2008.25 For technical reasons, Supplementary Tables 2, 3 and 4 were not published online. They now appear online at www.nature.com/mp.
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Article
Wavefront sensing for three-component three-dimensional flow velocimetry in microfluidics
We present the application of wavefront sensing to three-component, three-dimensional micro particle tracking velocimetry (μPTV). The technique is based upon examining the defocus of the wavefront scattered by...
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Article
Effects of scan circle displacement in optical coherence tomography retinal nerve fibre layer thickness measurement: a RNFL modelling study
To study the effect of optical coherence tomography (OCT) scan circle displacement on retinal nerve fibre layer (RNFL) measurement errors using cubic spline models.
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Article
Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo
Major depressive disorder (MDD) is a common complex trait with enormous public health significance. As part of the Genetic Association Information Network initiative of the US Foundation for the National Insti...
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Article
Genomewide association for schizophrenia in the CATIE study: results of stage 1
Little is known for certain about the genetics of schizophrenia. The advent of genomewide association has been widely anticipated as a promising means to identify reproducible DNA sequence variation associated...
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Article
Scaling laws of electron acceleration driven by an intense laser pulse
We studied the scaling laws for slow-electron acceleration driven by an intense laser pulse in a vacuum, the ponderomotive acceleration scenario (PAS) scheme. With 3D test particle simulation by numerically so...